Publications of the Week Immune Checkpoint TIM-3 Regulates Microglia and Alzheimer’s DiseaseKimura, K., et al. | April 17, 2025Microglia are the resident immune cells in the brain and have pivotal roles in neurodevelopment…karnottApril 17, 2025 Read More
Publications of the Week Lysine Vitcylation Is a Vitamin C-Derived Protein Modification That Enhances STAT1-Mediated Immune ResponseHe, X., et al. | April 15, 2025Vitamin C (vitC) is essential for health and shows promise in treating diseases like cancer,…karnottApril 15, 2025 Read More
Publications of the Week Molecular Basis for Shifted Receptor Recognition by an Encephalitic ArbovirusFan, X., et al. | April 11, 2025Western equine encephalitis virus (WEEV) is an arbovirus that historically caused large outbreaks of encephalitis…karnottApril 11, 2025 Read More
Publications of the Week Identification of a Molecular Resistor That Controls UCP1-Independent Ca2+ Cycling Thermogenesis in Adipose TissueAuger, C., et al. | April 8, 2025Adipose tissue thermogenesis contributes to energy balance via mitochondrial uncoupling protein 1 (UCP1) and UCP1-independent…karnottApril 8, 2025 Read More
Publications of the Week Functional Diversification of Dietary Plant Small Molecules by the Gut MicrobiomeKuziel, G., et al. | April 4, 2025Plants are composed of diverse secondary metabolites (PSMs), which are widely associated with human health.…karnottApril 4, 2025 Read More
Publications of the Week Enteric Neuronal Piezo1 Maintains Mechanical and Immunological Homeostasis by Sensing ForceXie, Z., et al. | April 2, 2025The gastrointestinal (GI) tract experiences a myriad of mechanical forces while orchestrating digestion and barrier…karnottApril 2, 2025 Read More
Publications of the Week Proliferation History and Transcription Factor Levels Drive Direct Conversion to Motor NeuronsWang, N., et al. | March 24, 2025The sparse and stochastic nature of conversion has obscured our understanding of how transcription factors…karnottMarch 24, 2025 Read More
Publications of the Week Simultaneous CRISPR Screening and Spatial Transcriptomics Reveal Intracellular, Intercellular, and Functional Transcriptional CircuitsBinan, L., et al. | March 21, 2025Pooled optical screens have enabled the study of cellular interactions, morphology, or dynamics at massive…karnottMarch 21, 2025 Read More
Publications of the Week A Torpor-Like State in Mice Slows Blood Epigenetic Aging and Prolongs HealthspanJayne, L., et al. | March 19, 2025Torpor and hibernation are extreme physiological adaptations of homeotherms associated with pro-longevity effects. Yet the…karnottMarch 19, 2025 Read More
Publications of the Week Analysis of Human Urinary Extracellular Vesicles Reveals Disordered Renal Metabolism in Myotonic Dystrophy Type 1Kumari, P., et al. | March 17, 2025Chronic kidney disease (CKD) and the genetic disorder myotonic dystrophy type 1 (DM1) each are…karnottMarch 17, 2025 Read More