Publications of the Week

Exocyst is a large multisubunit tethering complex essential for targeting and fusion of secretory vesicles…

Prion disease is a fatal neurodegenerative disease caused by the misfolding of prion protein (PrP)…

Genome editing using CRISPR-Cas systems is a promising avenue for the treatment of genetic diseases.…

An expanded repertoire of therapeutic tools is needed to explore and alter the function of…

Over a lifetime, hematopoietic stem cells (HSCs) adjust their lineage output to support age-aligned physiology.…

The coordinate regulation of metabolism and epigenetics to establish cell state-specific gene expression patterns during…

We developed a system utilizing rabies virus–based monosynaptic tracing to visualize neurons that synapse onto…

BCL11A is a transcription factor involved in the development of the brain and hematopoietic (blood)…

The introduction of immune checkpoint blockade (ICB) has markedly improved outcomes for advanced melanoma. However,…

The pathogenic mechanisms of many diseases are well understood at the molecular level, but there…