Currently there are no contraceptives capable of producing permanent sterilization in companion animals. Spaying, the surgical removal of the ovaries and uterus, is the most widely used strategy to control unwanted reproduction in female cats.
For the first time, researchers at Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB), and their collaborators have demonstrated that a single dose of anti-Müllerian hormone (AMH) gene therapy can induce long-term contraception in the domestic cat, potentially providing a safe and effective alternative to surgical spaying. The research is published in the latest issue of Nature Communications.
