Physician-scientists at the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute have discovered that a gene called FOXR2 that is normally turned off in most tissues in the body is activated in at least 70 percent of cancer types and eight percent of all individual tumors. Their study, recently published in Cancer Research, may help scientists better understand how a variety of cancers develop. The research team has already started working with chemists and structural biologists to figure out how to target this gene with possible new treatments.
