Tiny structures called nanoparticles can be used to carry substances to certain parts of the body—for example, to deliver a chemotherapy drug to a tumor. Although such “nanomedicine” offered hope for improving cancer therapeutics, the survival benefits of clinically approved nanomedicines are often modest when compared with conventional chemotherapy. New research published in the Journal of Controlled Release indicates that nanomedicine may provide additional benefits if it’s administered at lower, more frequent doses—called metronomic dosing—rather than the standard maximum tolerated dose of current treatments.