Furthering research into depression in women and the drugs used to treat it, the Women’s Health Program of the Massachusetts Life Sciences Center (MLSC) has awarded a grant to Jamie Maguire, a Kenneth and JoAnn G. Wellner Professor in the neuroscience department at Tufts University School of Medicine. She joins three other Tufts scientists awarded grants from the MLSC in 2021.
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A collaborative research effort at the Wyss Institute led by its Core Faculty members David Walt, Ph.D. and George Church, Ph.D. has developed new tools to measure and isolate tiny membrane-enclosed extracellular vesicles (EVs), which are shed by all cells in the body. EVs carry molecular cargo from their tissues of origin that could be used to diagnose diseases, including neurological diseases…
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The Craving State

For people struggling with substance use disorders — and there are about 35 million of them worldwide — treatment options are limited. Even among those who seek help, relapse is common. In the United States, an epidemic of opioid addiction has been declared a public health emergency. A 2019 survey found that 1.6 million people nationwide had an opioid use disorder, and…
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Janet Lubov, a dermatology research fellow at UMass Chan Medical School, hopes to help advance skin health in resource-limited communities, locally and globally, through sustainable and integrated approaches to clinical care, education, research, policy and advocacy. The Lupus Research Alliance has awarded Lubov a $15,000 Diversity Research Supplement Award for her work on cutaneous lupus erythematosus, a skin disease typically found on…
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In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens. Marked by a breakdown in the normal electrical patterns generated by the cells, they lose their specialized functions, start expanding into a tumor and spreading into and disrupting the function of other tissues — metastasis. As of yet, there are no clinically…
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When you touch something, whether stepping onto a sandy beach or stroking the back of a dog, sensations fly into your brain. You feel the coarse grain of the sand under your feet, the fluffiness of the fur on your hand. But you also bring a bit of yourself into the feeling: Along with the external stimulation from the beach…
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Growing up is a complex process for multi-celled organisms — plants included. In the days or weeks it takes to go from a seed to a sprout to a full plant, plants express hundreds of genes in different places at different times. In order to conduct this symphony of genes, plants rely in part on an elegant regulatory method called…
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Researchers in the lab of Bradley Pentelute, MIT professor of chemistry, have invented a fully automated fast-flow instrument that can synthesize peptide-nucleic acids in a single shot. By automating the process of synthesizing CPP-conjugated peptide-nucleic acids (PPNAs) using the robot dubbed “Tiny Tides” by the research team, typical PPNA synthesis time was reduced from multiple days to just two hours.…
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MIT seniors David Darrow and Tara Venkatadri have been selected as 2022 Churchill Scholars and will embark on a year of graduate studies in the U.K. starting next fall. James Diao, a graduate student in the Harvard-MIT Program in Health Sciences and Technology (HST), received the Kanders Churchill Scholarship in Science Policy. The Churchill Scholarship is a highly competitive fellowship…
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An additional “booster” dose of Moderna or Pfizer mRNA-based vaccine is needed to provide immunity against the Omicron variant of SARS-CoV-2, the virus that causes COVID-19, according to a study by researchers at the Ragon Institute of MGH, MIT and Harvard. The results of this study, reported in the journal Cell, indicate that traditional dosing regimens of COVID-19 vaccines available in the…
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