Local News How Climate Change is Helping the Spread of Infectious DiseasesBenchPress | June 27, 2024When we think of climate change, we often picture melting glaciers, raging wildfires and soaring…karnottJune 27, 2024 Read More
Publications of the Week Botensilimab Plus Balstilimab in Relapsed/Refractory Microsatellite Stable Metastatic Colorectal Cancer: A Phase 1 TrialBullock, A., et al. | June 27, 2024Microsatellite stable metastatic colorectal cancer (MSS mCRC; mismatch repair proficient) has previously responded poorly to…karnottJune 27, 2024 Read More
Local News Technologies Enable 3D Imaging of Whole Human Brain Hemispheres at Subcellular ResolutionMIT News | June 26, 2024Observing anything and everything within the human brain, no matter how large or small, while…karnottJune 26, 2024 Read More
Publications of the Week Strain-Specific Gut Microbial Signatures in Type 2 Diabetes Identified in a Cross-Cohort Analysis of 8,117 Metagenomes | June 26, 2024The association of gut microbial features with type 2 diabetes (T2D) has been inconsistent due…karnottJune 26, 2024 Read More
Publications of the Week Drug GRADE: An Integrated Analysis of Population Growth and Cell Death Reveals Drug-Specific and Cancer Subtype-Specific Response ProfilesSchwartz, H.R., et al. | June 29, 2020The typical measurement for evaluating drugs doesn’t distinguish between responses that are due to inhibition…eabramovichJune 29, 2020 Read More
Publications of the Week cGMP via PKG Activates 26S Proteasomes and Enhances Degradation of Proteins, Including Ones that Cause Neurodegenerative DiseasesVerPlank, J.J.S., et al. | June 26, 2020The authors demonstrate that agents that raise cGMP and activate the cGMP-dependent protein kinase (PKG),…eabramovichJune 26, 2020 Read More
Publications of the Week Inhibition of the Translesion Synthesis Polymerase REV1 Exploits Replication Gaps as a Cancer VulnerabilityNayak, S., et al. | June 22, 2020The authors reveal how a well described anti-cancer barrier, “the replication stress response,” is overcome…eabramovichJune 22, 2020 Read More
Publications of the Week Keap1 Mutation Renders Lung Adenocarcinomas Dependent on Slc33a1Romero, R., et al. | June 19, 2020Approximately 20–30% of human lung adenocarcinomas (LUADs) harbor mutations in Kelch-like ECH-associated protein 1 (KEAP1)…eabramovichJune 19, 2020 Read More
Local News Rapid DNA Sequencing Yields Timely Answers for Infant EpilepsyBoston Children's Hospital | August 31, 2023Treating children with epilepsy has traditionally been a matter of trial and error, trying different…sciencecityAugust 31, 2023 Read More
Local News Study Connects Neural Gene Expression Differences to Functional DistinctionsMIT News | August 30, 2023Figuring out how hundreds of different kinds of brain cells develop from their unique expression…sciencecityAugust 30, 2023 Read More
Local News Final Overall Study Analysis Continues to Show Benefit of Sacituzumab Govitecan in Advanced HR+ Breast CancerDana-Farber Cancer Institute | August 29, 2023A novel antibody-drug conjugate continues to demonstrate superior benefit for patients with HR+, HER2- metastatic…sciencecityAugust 29, 2023 Read More
Local News Can Better Data Predict Opioid Overdoses and Slow Infectious Disease Rates?Tufts Now | August 24, 2023In much the same way that meteorologists have become more sophisticated in forecasting the weather,…pthomsonAugust 24, 2023 Read More
Local News Jason Kim Discovery Could Lead to Potential Treatment for Metabolic Liver DiseaseUMass Chan Medical School | September 16, 2024Research from the lab of Jason Kim, PhD, professor of molecular medicine and medicine, identified…karnottSeptember 16, 2024 Read More
Local News Finding Some Stability in Adaptable BrainsMcGovern Institute | September 16, 2024One of the brain’s most celebrated qualities is its adaptability. Changes to neural circuits, whose…karnottSeptember 16, 2024 Read More
Local News Finding the WayMcGovern Institute | September 13, 2024When you arrive in a new city, every outing can be an exploration. You may…karnottSeptember 13, 2024 Read More