Would you buy and use a plasmid if it didn’t include any plasmid sequence data? Of course not. Unfortunately, the vast majority of antibodies are supplied with no sequence information, leading to problems with reproducibility and an inability to improve upon these critical research tools. Addgene is excited to announce that we have recently received a grant from the National Institutes of Health that will address this problem. The grant, which is part of the NIH’s Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative, will allow Addgene to create a much needed open-access recombinant antibody/affinity reagent resource for the neuroscience community called NABOR (Neuroscience AntiBody Open Resource). We are delighted to be partnered with Dr. James Trimmer of the University of California Davis School of Medicine on this grant. Dr. Trimmer has created thousands of high-quality antibodies/nanobodies for neuroscience research and is an expert at validating these tools. While the focus of the NABOR platform will be neuroscience reagents and data, the platform can be expanded for any recombinant antibody tool and therefore will grow to serve the entire scientific community.
