A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.
“Patients who received the kinase inhibitor cabozantinib in addition to checkpoint-blockers nivolumab and ipilimumab experienced significantly improved progression-free survival compared to those who received only nivolumab and ipilimumab,” said Toni Choueiri, MD. Choueiri, who is the director of the Lank Center for Genitourinary Cancer, will present results of the ongoing COSMIC-313 pivotal phase 3 clinical trial during the European Society of Medical Oncology (ESMO) Congress 2022, in Paris, France.
