Today, the Massachusetts Biotechnology Council (MassBio®) and Beacon Capital Partners announced a partnership to launch a nearly 4,000 square foot workforce training center at Southline Boston, the redevelopment project of the former Boston Globe building in Dorchester. Expected to open in Q4 of 2023, the MassBio Training Center will launch with three distinct fast-track certificate training programs that are purpose-built to…
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Clarivate has announced its Highly Cited Researchers™ 2022 list, which uses both quantitative and qualitative analysis to identify individuals from across the globe who have demonstrated significant and broad influence in their chosen field(s) of research. Each year’s list recognizes the authors of scientific papers that rank in the top 1% by citations in the Web of Science™ citation index over…
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At the Wyss Institute, we believe that breakthrough discoveries can’t change the world if they don’t leave the lab. Nobody exemplifies this more than our Lumineers, members of our community who have left academia and entered industry to translate their technologies into products that can transform healthcare and sustainability. The Institute developed a culture of intense collaboration between aspiring life science…
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Can AI Transform the Way We Discover New Drugs?

The world’s aging population, the growing burden of chronic and infectious diseases, and the emergence of novel pathogens have made the need for new treatments more urgent than ever. Yet, discovering a new drug and bringing it to market is a long, arduous, and expensive journey marked by many failures and few successes. Artificial intelligence has been long deemed the answer to…
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Wasting Muscles Built Back Better

Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age. Muscle atrophy, how clinicians refer to the phenomenon, is also a debilitating symptom in patients suffering from neurological disorders, such as amyotrophic lateral sclerosis (ALS) and multiple…
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Over the past two years, Boston University’s Clinical Testing Laboratory has processed an extraordinary number of COVID-19 tests—more than two million. At the pandemic’s peak, the lab’s eight state-of-the-art, liquid-handling robots—the indefatigable heart of a fully automated diagnostic facility—were running more than 6,000 tests a day, returning results in 24 hours, often less. That’s a lot of swabbed noses. Now, with those…
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Bioelectric Regulation of Intestinal Stem Cells

Ion channels, pumps, and exchangers regulate the transport of ions, such as Na+, Cl–, K+, and Ca2+, in and out of cells, and gap junctions allow the movement of ions across cells. Ion imbalance is highly associated with intestinal disorders and even cancer; therefore, a genetic model capable of decoding in vivo how ion regulation affects intestinal stem cell proliferation could have…
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Dr. Heidi Greulich's group is interested in understanding the mechanism of action of velcrin compounds, which kill cancer cells expressing elevated levels of PDE3A and SLFN12 by inducing PDE3A-SLFN12 complex formation, which in turn upregulates the RNase activity of SLFN12.  They are also interested in leveraging the PDE3A-SLFN12 interaction to develop a cancer therapeutic.
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Amanda Whipple Receives R35 Grant from the NIH

MCB faculty Amanda Whipple has received an R35 Maximizing Investigators’ Research Award (MIRA) from the NIH. The award provides five years of funding to promising early career PIs, with the goal of ensuring recipients’ stability and flexibility as their labs branch out in pursuit of new research questions. “Receiving a five-year award from the NIH feels like a special milestone for a new lab,…
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The four inaugural recipients of the Lubin Family Foundation Scholar Award have been announced by Dana-Farber Cancer Institute and the Richard K. Lubin Family Foundation. Lubin Scholars are among the most promising physician-scientists pursuing cancer-relevant basic or translational laboratory-based research, on track to becoming the next generation of leaders in cancer research.
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