Local News Curbing Blood Cancers by Teaching Immune Cells to Kill Mutant Stem CellsBoston Children's Hospital | September 23, 2024Blood stem cells, which give rise to all of our blood cell types, undergo a…karnottSeptember 23, 2024 Read More
Awards Alanna Carey Receives NIH Blueprint and BRAIN Initiative D-SPAN AwardBoston University Biology | September 20, 2024Alanna Carey, a PhD student in the Chen Lab, recently received the National Institutes of…karnottSeptember 20, 2024 Read More
Awards Freeman and Sharpe Receive Hamburg Award from National Academy of Medicine for Discoveries Leading to New, Effective ImmunotherapiesDana-Farber Cancer Institute | September 20, 2024The National Academy of Medicine (NAM) today announced that Gordon Freeman and Arlene Sharpe are…karnottSeptember 20, 2024 Read More
Publications of the Week Intercellular Nanotube-Mediated Mitochondrial Transfer Enhances T Cell Metabolic Fitness and Antitumor EfficacyBaldwin, J., et al. | September 20, 2024Mitochondrial loss and dysfunction drive T cell exhaustion, representing major barriers to successful T cell-based immunotherapies. Here,…karnottSeptember 20, 2024 Read More
Publications of the Week Chemokine CCL5 Promotes Robust Optic Nerve Regeneration and Mediates Many of the Effects of CNTF Gene TherapyXie, L., et al. | March 11, 2021Ciliary neurotrophic factor (CNTF) is a leading therapeutic candidate for several ocular diseases and induces…sciencecityMarch 11, 2021 Read More
Publications of the Week Increased Stem Cell Proliferation in Atherosclerosis Accelerates Clonal HematopoiesisHeyde, A., et al. | March 10, 2021Clonal hematopoiesis, a condition in which individual hematopoietic stem cell clones generate a disproportionate fraction…sciencecityMarch 10, 2021 Read More
Publications of the Week Cryo-EM Structure of an Activated GPCR-G Protein Complex in Lipid NanodiscsZhang, M., et al. | March 5, 2021G-protein-coupled receptors (GPCRs) are the largest superfamily of transmembrane proteins and the targets of over…sciencecityMarch 5, 2021 Read More
Publications of the Week Clinical Implications of Colorectal Cancer Stem Cells in the Age of Single-Cell Omics and Targeted TherapiesFrank, M.H., et al. | March 2, 2021The cancer stem cell (CSC) concept emerged from the recognition of inherent tumor heterogeneity and…sciencecityMarch 2, 2021 Read More
Local News Cancer Test Shows Promise for Bringing the Benefits of Immunotherapy to More PatientsBrigham and Women's Hospital | January 5, 2024Brigham researchers’ findings from next-generation sequencing suggest that revising current cancer care guidelines could allow…karnottJanuary 5, 2024 Read More
Local News Newly Developed Model-Based Analysis Reveals Protein Proofreading in Ribosome BiogenesisMIT Biology | January 5, 2024One of the most critical complexes in cells is the ribosome, the large and elaborate…karnottJanuary 5, 2024 Read More
Local News Anthony Rothschild to Lead Psilocybin Study for Treatment-Resistant Depression at UMass ChanUMass Chan Medical School | January 5, 2024Anthony Rothschild, MD, the Irving S. and Betty Brudnick Chair in Psychiatry and professor of psychiatry, will…karnottJanuary 5, 2024 Read More
Local News Mass General Scientists Predict Big ‘Breakthroughs’ In Medicine For 2024Bench Press | January 4, 2024As we eagerly wait for the arrival of the new year, our curiosity turns to…karnottJanuary 4, 2024 Read More
Local News Groundbreaking Discovery Uncovers Achilles’ Heel of Malaria ParasiteRagon Institute | November 28, 2024A collaborative effort between researchers from Uganda, Tanzania, the US, Spain, and Denmark has resolved…karnottNovember 28, 2024 Read More
Awards Wyss Institute’s iNodes Team Receives ARPA-H Sprint for Women’s Health Award to Advance the First Implantable Immune Organs to Treat Ovarian CancerWyss Institute | November 27, 2024Ovarian cancer is more deadly than any other type of female reproductive organ cancer. It…karnottNovember 27, 2024 Read More
Publications of the Week Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death That Combines with Interferon Alpha Therapy for Tumor ControlStinson, J., et al. | November 27, 2024Although heightened intratumoral levels of reactive oxygen species (ROS) are typically associated with a suppressive…karnottNovember 27, 2024 Read More