Local News Overcoming Drug Resistance with EAI-432, an Allosteric EGFR Inhibitor for Non-Small Cell Lung CancerDana-Farber Cancer Institute | December 4, 2023Researchers at Dana-Farber Cancer Institute have developed a promising new drug candidate, EAI-432, to treat…sciencecityDecember 4, 2023 Read More
Local News What Shapes Your Dog’s PersonalityThe Harvard Gazette | December 1, 2023Some dogs love to play fetch, while others watch the tennis ball roll by with…sciencecityDecember 1, 2023 Read More
Local News New Clues Into the Head-Scratching Mystery of ItchHarvard Medical School | December 1, 2023Scientists at Harvard Medical School have shown for the first time that a common skin…sciencecityDecember 1, 2023 Read More
Local News Cell Fate Choice during Adult Regeneration Is Highly Disorganized, New Study FindsWhitehead Institute | November 30, 2023A team of scientists at the Whitehead Institute for Biomedical Research and MIT has spatially mapped…sciencecityNovember 30, 2023 Read More
Local News Researchers Develop New Method for Prenatal Genetic TestingMassachusetts General Hospital | November 30, 2023A team of investigators from Massachusetts General Hospital (MGH), Brigham and Women’s Hospital (BWH), and…sciencecityNovember 30, 2023 Read More
Publications of the Week Allosteric PI3K-Alpha Inhibition Overcomes On-Target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.Varkaris, A., et al. | November 24, 2023PIK3CA mutations occur in ~8% of cancers, including ~40% of HR-positive breast cancers, where the…sciencecityNovember 24, 2023 Read More
Publications of the Week Targeting DNA Methylation and B7-H3 in RB1-Deficient and Neuroendocrine Prostate CancerYamada, Y., et al. | November 22, 2023DNA methyltransferases (DNMTs) are increased in neuroendocrine prostate cancer (NEPC), an aggressive cancer associated with…sciencecityNovember 22, 2023 Read More
Local News What Human Diseases Can Teach Us About the Immune SystemHarvard Medical School | November 21, 2023The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks…sciencecityNovember 21, 2023 Read More
Awards Marcus Ruscetti Receives American Cancer Society Award for Prostate Cancer ResearchUMass Chan Medical School | November 20, 2023Marcus Ruscetti, PhD, assistant professor of molecular, cell & cancer biology, received a Research Scholar…sciencecityNovember 20, 2023 Read More
Publications of the Week Knockout or Inhibition of USP30 Protects Dopaminergic Neurons in a Parkinson’s Disease Mouse ModelFang, T., et al. | November 20, 2023Mutations in SNCA, the gene encoding α-synuclein (αSyn), cause familial Parkinson’s disease (PD) and aberrant…sciencecityNovember 20, 2023 Read More