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Webinar: Targeted Protein Degradation Virtual Symposium
July 15, 2020
The symposium will bring together insights on:
- Critical assessment of the field
- PROTAC® design, discovery and development
- Innovative new research tools
- Expanding the E3 ligase toolbox
We hope you will join us for what will be a fascinating and informative symposium.
Targeted Protein Degradation (TPD) is a technology that harnesses small molecule modalities (molecular glues, PROTAC® Degraders, SNIPERS etc) to achieve selective knockdown of target proteins within cells.
Heterobifunctional Degraders represent an exciting new modality, repurposing small molecule ligands to achieve selective degradation (knock-down) of target proteins and offering the potential to expand the druggable proteome.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
|Time (BST / EDT)||Speaker||Talk Title|
|3pm / 10am||Dr. Hannah Maple||Welcome / Introduction|
|3:10pm / 10:10am||Dr. Milka Kostic||Seeing the forest for the trees in targeted protein degradation|
|3:35pm / 10:35am||Dr. Alex Bullock||Expanding the toolbox for PROTAC development|
|4pm / 11am||Dr. Cristina Mayor-Ruiz||Rational discovery of molecular glue degraders via scalable chemical profiling|
|4:25pm / 11:25am Short Break|
|4:30pm / 11:30am||Dr. Behnam Nabet
Dr. Fleur Ferguson
|Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules|
|5pm / 12pm||Dr. Nicole Trainor||Structure-based approaches to accelerate PROTAC discovery|
|5:25pm / 12:25pm||Dr. Scott Edmondson||Lessons Learned in the Design of Oral PROTACs|
|5:50pm / 12:50pm||Dr. Hannah Maple||Closing remarks|