Understanding how the brain senses and responds to internal physiological states—like hunger, thirst, and inflammation—is vital to survival. Recent advances are revealing the circuits that link body and brain to maintain homeostasis and shape behavior. The Picower Institute’s Fall 2025 Symposium, “Circuits of Survival and Homeostasis,” gathers leading researchers exploring how these systems monitor, regulate, and repair fundamental physiological functions, offering insights into their mechanisms and potential therapeutic targets. More information and registration to come in late August.