Virtual screening can be a very efficient way to identify initial lead molecules or a back-up series for a drug discovery program. Obvious advantages include access to increased molecular diversity, an ability to find new IP, savings in time and ultimately cost. One of the most critical challenges of virtual screening is determining the most effective screening strategy: this implies working through the data and detail of the experimental design to achieve the desired outcome for any given starting point.

In this webinar we will show how Flare™, Forge™ and Blaze™ can be used to analyze and develop an appropriate virtual screening strategy for complex target systems for which no simple small ligands exists, and how that can be worked into an effective virtual screen.