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BioMaking Solutions: COVID-19 Seminar – Virus-like DNA Nanoparticle Vaccine for COVID-19

July 16, 2020

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COVID-19: BioMaking Solutions – Dr. Mark Bathe, MIT Department of Biological Engineering, “Virus-like DNA Nanoparticle Vaccine for COVID-19”

Three coronaviruses have crossed the species barrier to infect humans to cause deadly pneumonia in recent years, SARS-CoV, MERS-CoV, and most recently SARS-CoV-2, causing COVID-19, which is an ongoing pandemic that has killed over 375,000 people worldwide as of June 1, 2020. To date, there is no approved vaccine against any human-infecting coronavirus. I will present our approach to enhancing the efficacy of subunit vaccines by formulating heterovalent immunogens in a multivalent, nanoparticulate form using virus-like DNA nanoparticles to enhance B cell receptor signaling for the production of broadly neutralizing antibodies for the current, and any future, coronavirus threat.

Jul 16, 2020 12:00 PM in Eastern Time (US and Canada)


July 16
12:00 pm - 1:00 pm




MIT Biomakers