Publications of the Week KDM6A Epigenetically Regulates Subtype Plasticity in Small Cell Lung CancerDuplaquet, L., et al. | August 22, 2023Small cell lung cancer (SCLC) exists broadly in four molecular subtypes: ASCL1, NEUROD1, POU2F3 and…pthomsonAugust 22, 2023 Read More
Local News Moving the Needle on Monitoring Skin CancerWyss Institute | August 22, 2023atients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start…pthomsonAugust 22, 2023 Read More
Local News Cell Therapy That Repairs Cornea Damage with Patient’s Own Stem Cells Achieves Positive Phase I Trial ResultsDana-Farber Cancer Institute | August 22, 2023A team led by researchers from Dana-Farber Cancer Institute and Mass Eye and Ear, a…pthomsonAugust 22, 2023 Read More
AwardsFeatured Awards Pamela Garcia Lopez Recipient of Kilachand Doctoral FellowshipBoston University Biology | August 16, 2023Pamela Garcia Lopez of the Siggers Lab recently received the Kilachand Doctoral Fellowship. This fellowship is awarded…pthomsonAugust 16, 2023 Read More
Publications of the Week Targeting the HIF2–VEGF Axis in Renal Cell CarcinomaChoueiri, T.K., & Kaelin Jr., W.G. | October 9, 2020Insights into the role of the tumor suppressor pVHL in oxygen sensing motivated the testing…eabramovichOctober 9, 2020 Read More
Publications of the Week Divergent Roles of PI3K Isoforms in PTEN-Deficient GlioblastomasXie, S., et al. | October 8, 2020Loss of PTEN, the negative regulator of PI3K activity, is frequent in glioblastomas (GBMs). However,…eabramovichOctober 8, 2020 Read More
Publications of the Week pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to ExerciseReddy, A., et al. | October 1, 2020The authors discovered that exercising muscle selectively releases the mitochondrial metabolite succinate. Once released, succinate…eabramovichOctober 1, 2020 Read More
Publications of the Week HDAC6 Mediates an Aggresome-Like Mechanism for NLRP3 and Pyrin Inflammasome ActivationMagupalli, V.G., et al. | September 28, 2020Canonical inflammasomes are multicomponent protein complexes that play key roles in immune surveillance of infections…eabramovichSeptember 28, 2020 Read More
Local News The Case for Female Mice in Neuroscience ResearchHarvard Medical School | March 10, 2023Mice have long been a central part of neuroscience research, providing a flexible model that…pthomsonMarch 10, 2023 Read More
Local News How Does Infection Change Social Behavior?The Harvard Gazette | March 9, 2023As COVID has demonstrated, when pathogens are moving through the population, we adjust, limiting interactions,…pthomsonMarch 9, 2023 Read More
Local News How Gut Microbes Help Mend Damaged MusclesHarvard Medical School | March 8, 2023The human immune system is incredibly versatile. Among its most skilled multitaskers are T cells,…pthomsonMarch 8, 2023 Read More
Local News Anticipating and Countering Infectious DiseasesWhitehead Institute | March 8, 2023Climate change and economic development are, together, rapidly altering the ecological niches of thousands of…pthomsonMarch 8, 2023 Read More
Local News Staying Ahead of Virus MutationsThe Harvard Gazette | October 16, 2023The COVID-19 pandemic seemed like a never-ending parade of SARS-CoV-2 variants, each equipped with new…sciencecityOctober 16, 2023 Read More
Publications of the Week Cell-Type-Specific Regulation of APOE and CLU Levels in Human Neurons by the Alzheimer’s Disease Risk Gene SORL1Lee, H., et al. | October 13, 2023SORL1 is implicated in the pathogenesis of Alzheimer’s disease (AD) through genetic studies. To interrogate…sciencecityOctober 13, 2023 Read More
Awards BU Researcher Awarded $3.7 Million to Study How Endothelial Cell Health Impacts DiseaseBoston University | October 13, 2023Naomi Hamburg, MD, the Joseph A. Vita Professor of Medicine at Boston University Chobanian &…sciencecityOctober 13, 2023 Read More