Local News Maintaining Fertility Requires Uneven Division of DNAWhitehead Institute | November 16, 2023Germline stem cells are the pool of stem cells capable of becoming eggs or sperm.…sciencecityNovember 16, 2023 Read More
Publications of the Week DGKα/ζ Inhibitors Combine with PD-1 Checkpoint Therapy to Promote T Cell–Mediated Antitumor ImmunityWichroski, M., et al. | November 16, 2023Read the Publication This week, Science in Boston profiles Dr. Michael Wichroski (pictured). Dr. Wichroski…sciencecityNovember 16, 2023 Read More
Publications of the Week Liquid Biopsy Epigenomic Profiling for Cancer SubtypingBaca, S., et al. | November 14, 2023Although circulating tumor DNA (ctDNA) assays are increasingly used to inform clinical decisions in cancer…sciencecityNovember 14, 2023 Read More
Local News Research Spotlight: Creating Microfluidic Transistors That Control the Movement of Fluids to Autonomously Execute Miniature Lab OperationsMassachusetts General Hospital | November 14, 2023Kaustav Gopinathan, an MD-PhD student in the Center for Engineering in Medicine and Surgery at…sciencecityNovember 14, 2023 Read More
Publications of the Week Genome-Wide Analysis of Somatic Noncoding Mutation Patterns in CancerDietlein, F., et al. | April 13, 2022Numerous large-scale efforts have been undertaken to catalog and understand the biology of cancer-associated mutations…pthomsonApril 13, 2022 Read More
Publications of the Week Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene ExpressionHemming, M. L., et al. | April 12, 2022Leiomyosarcoma (LMS) is a neoplasm characterized by smooth muscle differentiation, complex copy-number alterations, tumor suppressor…pthomsonApril 12, 2022 Read More
Publications of the Week Types and Functions of Heterogeneity in MycobacteriaChung, E. S., et al. | April 8, 2022The remarkable ability of Mycobacterium tuberculosis to survive attacks from the host immune response and drug treatment…pthomsonApril 8, 2022 Read More
Publications of the Week Stitchr: Stitching Coding TCR Nucleotide Sequences from V/J/CDR3 InformationHeather, J. M., et al. | April 5, 2022The study and manipulation of T cell receptors (TCRs) is central to multiple fields across…pthomsonApril 5, 2022 Read More
Local News From Bench to Bedside: A Promising Option for Unremitting Ulcerative ColitisBoston Children's Hospital | July 21, 2023Many existing treatments for inflammatory bowel disease, like Remicade® and Humira®, work by blocking inflammatory…pthomsonJuly 21, 2023 Read More
Local News ‘Doctors Need To Get on Top of This’: GPT-4 Displays Bias in Medical TasksStat | July 21, 2023Diagnosis is an especially tantalizing application for generative AI: Even when given tough cases that…pthomsonJuly 21, 2023 Read More
Local News Aspartame: What You Need To KnowDana-Farber Cancer Institute | July 21, 2023Alongside gasoline engine exhaust and radiofrequency waves from cell phones, aspartame, the sweetener found in…pthomsonJuly 21, 2023 Read More
Local News Seeking a Path Forward for Custom Genetic TreatmentsBoston Children's Hospital | July 20, 2023In 2018, at age 7, Mila Makovec became the world’s first person to be treated…pthomsonJuly 20, 2023 Read More
Publications of the Week Nanoparticle-Mediated Delivery of Anti-PU.1 siRNA via Localized Intracisternal Administration Reduces NeuroinflammationRalvenius, W., et al. | December 15, 2023Neuroinflammation is a hallmark of neurodegenerative disorders including Alzheimer's disease (AD). Microglia, the brain's immune…karnottDecember 15, 2023 Read More
Local News Bluebird Bio Receives US FDA Nod for Sickle Cell TherapyBioProcess International | December 15, 2023The US Food and Drug Administration (FDA) has approved bluebird’s Lyfgenia (lovotibeglogene autotemcel) for the…karnottDecember 15, 2023 Read More
Local News Demystifying a Mammal’s Brain, Cell by CellThe Harvard Gazette | December 14, 2023A group of scientists, including several at Harvard, have dived deeper into the mammalian brain…karnottDecember 14, 2023 Read More