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BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20210324T170000
DTEND;TZID=America/Vancouver:20210324T180000
DTSTAMP:20260414T034911
CREATED:20210301T181051Z
LAST-MODIFIED:20210301T181051Z
UID:13142-1616605200-1616608800@scienceinboston.com
SUMMARY:Biomedical Informatics Entrepreneurs Salon
DESCRIPTION:When\nWednesday\, March 24\, 2021\, 5 – 6pm\n\n\nWhere\nZoom\n\n\nSpeaker Name\nLevi Garraway\n\n\nSpeaker Title\nChief Medical Officer\n\n\nSpeaker Institution\nRoche and Genentech\n\n\nSpeaker Website\nwww.roche.com…\n\n\nRSVP Required\nYes\n\n\nDepartment/Office\nBiomedical Informatics\, Office of Technology Development\n\n\n\n\n\n\nDetails\n\nBIES is a monthly conversation about medicine\, biology\, computers\, and entrepreneurship. \nRegistration and more info to come!
URL:https://scienceinboston.com/event/biomedical-informatics-entrepreneurs-salon/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20210324T170000
DTEND;TZID=America/Vancouver:20210324T180000
DTSTAMP:20260414T034911
CREATED:20210301T181051Z
LAST-MODIFIED:20210301T181051Z
UID:27664-1616605200-1616608800@scienceinboston.com
SUMMARY:Biomedical Informatics Entrepreneurs Salon
DESCRIPTION:When\nWednesday\, March 24\, 2021\, 5 – 6pm\n\n\nWhere\nZoom\n\n\nSpeaker Name\nLevi Garraway\n\n\nSpeaker Title\nChief Medical Officer\n\n\nSpeaker Institution\nRoche and Genentech\n\n\nSpeaker Website\nwww.roche.com…\n\n\nRSVP Required\nYes\n\n\nDepartment/Office\nBiomedical Informatics\, Office of Technology Development\n\n\n\n\n\n\nDetails\n\nBIES is a monthly conversation about medicine\, biology\, computers\, and entrepreneurship. \nRegistration and more info to come!
URL:https://scienceinboston.com/event/biomedical-informatics-entrepreneurs-salon-3/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210325T160000
DTEND;TZID=America/New_York:20210325T170000
DTSTAMP:20260414T034911
CREATED:20210322T175109Z
LAST-MODIFIED:20210322T175109Z
UID:13479-1616688000-1616691600@scienceinboston.com
SUMMARY:Dental Regenerative Medicine: Advancing Science to Help Patients
DESCRIPTION:William V. Giannobile \nDean\, Harvard School of Dental Medicine \nDr. William Giannobile\, dean of Harvard School of Dental Medicine (HSDM)\, is a leader in the field of periodontology and an internationally recognized scholar in oral regenerative medicine\, tissue engineering\, and precision medicine. He is an alumnus of HSDM\, with an advanced degree in periodontology and oral biology. \nThis talk will highlight tissue engineering strategies using biologics\, cellular and gene therapeutics that are now beginning to enter the clinical arena. These technologies include the use of 3D printing on growth factors to rebuild tissues around teeth and replacements in the jaws such as dental implants. \nHOST: \nDavid J. Mooney\, PhD \nFounding Core Faculty & Lead\, \nImmuno-Materials\, Wyss Institute at Harvard University; \nRobert P. Pinkas Family Professor of Bioengineering\, \nHarvard John A. Paulson School of Engineering and Applied Sciences
URL:https://scienceinboston.com/event/dental-regenerative-medicine-advancing-science-to-help-patients/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210325T160000
DTEND;TZID=America/New_York:20210325T170000
DTSTAMP:20260414T034911
CREATED:20210322T175109Z
LAST-MODIFIED:20210322T175109Z
UID:27677-1616688000-1616691600@scienceinboston.com
SUMMARY:Dental Regenerative Medicine: Advancing Science to Help Patients
DESCRIPTION:William V. Giannobile \nDean\, Harvard School of Dental Medicine \nDr. William Giannobile\, dean of Harvard School of Dental Medicine (HSDM)\, is a leader in the field of periodontology and an internationally recognized scholar in oral regenerative medicine\, tissue engineering\, and precision medicine. He is an alumnus of HSDM\, with an advanced degree in periodontology and oral biology. \nThis talk will highlight tissue engineering strategies using biologics\, cellular and gene therapeutics that are now beginning to enter the clinical arena. These technologies include the use of 3D printing on growth factors to rebuild tissues around teeth and replacements in the jaws such as dental implants. \nHOST: \nDavid J. Mooney\, PhD \nFounding Core Faculty & Lead\, \nImmuno-Materials\, Wyss Institute at Harvard University; \nRobert P. Pinkas Family Professor of Bioengineering\, \nHarvard John A. Paulson School of Engineering and Applied Sciences
URL:https://scienceinboston.com/event/dental-regenerative-medicine-advancing-science-to-help-patients-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210329T170000
DTEND;TZID=America/New_York:20210329T183000
DTSTAMP:20260414T034911
CREATED:20210322T185134Z
LAST-MODIFIED:20210322T185134Z
UID:13475-1617037200-1617042600@scienceinboston.com
SUMMARY:MIT Research Slam Competition Public Showcase
DESCRIPTION:Interested in hearing about cool & cutting-edge research at MIT from excellent science communicators? Register to attend MIT’s first Research Slam Showcase\, a public showcase of research by MIT graduate students & scholars with prizes for the best communicators. The showcase will feature participants explaining their research and its importance in 3 minutes or less\, with judging by an expert panel of judges and by YOU\, the audience. \nThe 90-minute program will include live viewing of finalist Slam submissions\, evaluation & feedback from judges\, and a declaration of winners. Attendees can join in the fun by asking questions to participants\, leaving comments\, and voting for the audience-choice awards. So\, come join us for a celebration of innovative research and clear communication at MIT! \nThe Slam Showcase is free and open to everybody and anybody\, so please share with your friends & family. You can find more information at researchslam.mit.edu\, and please don’t hesitate to contact us with any questions! \nRegister to attend at: https://mit.zoom.us/webinar/register/WN_hI6g1uIxQh6xAWchqpkV1w
URL:https://scienceinboston.com/event/mit-research-slam-competition-public-showcase/
LOCATION:Online
ATTACH;FMTTYPE=image/png:https://scienceinboston.com/wp-content/uploads/sites/6/2021/03/3MT-Research-Slam-Logo-Final.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210329T170000
DTEND;TZID=America/New_York:20210329T183000
DTSTAMP:20260414T034911
CREATED:20210322T185134Z
LAST-MODIFIED:20210322T185134Z
UID:27676-1617037200-1617042600@scienceinboston.com
SUMMARY:MIT Research Slam Competition Public Showcase
DESCRIPTION:Interested in hearing about cool & cutting-edge research at MIT from excellent science communicators? Register to attend MIT’s first Research Slam Showcase\, a public showcase of research by MIT graduate students & scholars with prizes for the best communicators. The showcase will feature participants explaining their research and its importance in 3 minutes or less\, with judging by an expert panel of judges and by YOU\, the audience. \nThe 90-minute program will include live viewing of finalist Slam submissions\, evaluation & feedback from judges\, and a declaration of winners. Attendees can join in the fun by asking questions to participants\, leaving comments\, and voting for the audience-choice awards. So\, come join us for a celebration of innovative research and clear communication at MIT! \nThe Slam Showcase is free and open to everybody and anybody\, so please share with your friends & family. You can find more information at researchslam.mit.edu\, and please don’t hesitate to contact us with any questions! \nRegister to attend at: https://mit.zoom.us/webinar/register/WN_hI6g1uIxQh6xAWchqpkV1w
URL:https://scienceinboston.com/event/mit-research-slam-competition-public-showcase-2/
LOCATION:Online
ATTACH;FMTTYPE=image/png:https://scienceinboston.com/wp-content/uploads/sites/6/2021/03/3MT-Research-Slam-Logo-Final.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210330T160000
DTEND;TZID=America/New_York:20210330T170000
DTSTAMP:20260414T034911
CREATED:20210326T232438Z
LAST-MODIFIED:20210326T232438Z
UID:13607-1617120000-1617123600@scienceinboston.com
SUMMARY:Biology Colloquium Series (Dr. Cassandra Extavour)
DESCRIPTION:Speaker: Dr. Cassandra Extavour\, Harvard University. Hosted by Ruth Lehmann. Title: “Take your place! A new mechanism driving nuclear movement during embryogenesis.” The Biology Colloquium is a weekly seminar held throughout the academic year\, featuring distinguished speakers in many areas of the biological sciences\, from universities and institutions worldwide. More information on speakers\, their affiliations\, and titles of their talks will be added as available. The Colloquium will zoom at 4:00PM  Tuesdays during the school year. Contact: Linda Earle lkn@mit.edu
URL:https://scienceinboston.com/event/biology-colloquium-series-dr-cassandra-extavour/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210330T160000
DTEND;TZID=America/New_York:20210330T170000
DTSTAMP:20260414T034911
CREATED:20210326T232438Z
LAST-MODIFIED:20210326T232438Z
UID:27685-1617120000-1617123600@scienceinboston.com
SUMMARY:Biology Colloquium Series (Dr. Cassandra Extavour)
DESCRIPTION:Speaker: Dr. Cassandra Extavour\, Harvard University. Hosted by Ruth Lehmann. Title: “Take your place! A new mechanism driving nuclear movement during embryogenesis.” The Biology Colloquium is a weekly seminar held throughout the academic year\, featuring distinguished speakers in many areas of the biological sciences\, from universities and institutions worldwide. More information on speakers\, their affiliations\, and titles of their talks will be added as available. The Colloquium will zoom at 4:00PM  Tuesdays during the school year. Contact: Linda Earle lkn@mit.edu
URL:https://scienceinboston.com/event/biology-colloquium-series-dr-cassandra-extavour-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210401T120000
DTEND;TZID=America/New_York:20210401T130000
DTSTAMP:20260414T034911
CREATED:20210322T203008Z
LAST-MODIFIED:20210322T203030Z
UID:13486-1617278400-1617282000@scienceinboston.com
SUMMARY:Open Box Science Thursday Webinar Series: Targeting Microglia and Macrophages in Aging and Neurodegeneration
DESCRIPTION:SPEAKERS:\nParas Minhas | Stanford University\nRestoring metabolism of myeloid cells reverses cognitive decline in ageing (Nature 2021) \nAude Chiot | Oregon Health & Science University\nModifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival (Nat Neurosci 2021) \nMODERATOR:\nLindsay Welikovitch | Massachusetts General Hospital
URL:https://scienceinboston.com/event/open-box-science-thursday-webinar-series-targeting-microglia-and-macrophages-in-aging-and-neurodegeneration/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210401T120000
DTEND;TZID=America/New_York:20210401T130000
DTSTAMP:20260414T034911
CREATED:20210322T203008Z
LAST-MODIFIED:20210322T203008Z
UID:27679-1617278400-1617282000@scienceinboston.com
SUMMARY:Open Box Science Thursday Webinar Series: Targeting Microglia and Macrophages in Aging and Neurodegeneration
DESCRIPTION:SPEAKERS:\nParas Minhas | Stanford University\nRestoring metabolism of myeloid cells reverses cognitive decline in ageing (Nature 2021) \nAude Chiot | Oregon Health & Science University\nModifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival (Nat Neurosci 2021) \nMODERATOR:\nLindsay Welikovitch | Massachusetts General Hospital
URL:https://scienceinboston.com/event/open-box-science-thursday-webinar-series-targeting-microglia-and-macrophages-in-aging-and-neurodegeneration-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20210405T140000
DTEND;TZID=America/Vancouver:20210405T150000
DTSTAMP:20260414T034911
CREATED:20210315T154739Z
LAST-MODIFIED:20210315T154935Z
UID:13361-1617631200-1617634800@scienceinboston.com
SUMMARY:Ensuring Equitable Access To New Gene Therapies
DESCRIPTION:While recent clinical trials of innovative\, new gene therapies show incredible promise for patients who have faced a lifetime of unmet medical needs\, the biggest challenge for these therapies is yet to come – ensuring equitable access. \nA critical moment for this issue could be the development of new therapies for sickle cell disease\, which affects approximately one in 365 Black Americans. What can the life sciences do to ensure that all patients have access to what could be life-changing medicines? \nIn this month’s Make Shift Happen\, panelists from the gene therapy sector and patient advocacy space will discuss: \n\nThe current state of ED&I in therapeutic development\nTaking a patient-centric approach to developing new gene therapies\nChallenges and opportunities for improving therapeutic accessibility
URL:https://scienceinboston.com/event/ensuring-equitable-access-to-new-gene-therapies/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20210405T140000
DTEND;TZID=America/Vancouver:20210405T150000
DTSTAMP:20260414T034911
CREATED:20210315T154739Z
LAST-MODIFIED:20210315T154739Z
UID:27671-1617631200-1617634800@scienceinboston.com
SUMMARY:Ensuring Equitable Access To New Gene Therapies
DESCRIPTION:While recent clinical trials of innovative\, new gene therapies show incredible promise for patients who have faced a lifetime of unmet medical needs\, the biggest challenge for these therapies is yet to come – ensuring equitable access. \nA critical moment for this issue could be the development of new therapies for sickle cell disease\, which affects approximately one in 365 Black Americans. What can the life sciences do to ensure that all patients have access to what could be life-changing medicines? \nIn this month’s Make Shift Happen\, panelists from the gene therapy sector and patient advocacy space will discuss: \n\nThe current state of ED&I in therapeutic development\nTaking a patient-centric approach to developing new gene therapies\nChallenges and opportunities for improving therapeutic accessibility
URL:https://scienceinboston.com/event/ensuring-equitable-access-to-new-gene-therapies-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210405T160000
DTEND;TZID=America/New_York:20210405T170000
DTSTAMP:20260414T034911
CREATED:20210325T165855Z
LAST-MODIFIED:20210325T165912Z
UID:13563-1617638400-1617642000@scienceinboston.com
SUMMARY:Joshua Sanes | Cell Types as Building Blocks of Neural Circuits
DESCRIPTION:Join us for the 2021 Edward M. Scolnick Prize in Neuroscience Lecture \nCell Types as Building Blocks of Neural Circuits \nJoshua Sanes\, Harvard University \nAbstract: Classification of neurons was a major preoccupation of Cajal\, but later came to be viewed as a fairly boring enterprise. Over the past few decades\, however\, inability to define neuronal types emerged as a major bottleneck in analysis of neural circuits and brain disorders. The introduction of high throughput single cell RNAseq in 2015 provided a new way to approach this problem. I will describe its use to generate an atlas of 130 cell types from mouse retina\, a particularly accessible part of the brain\, and then show how the atlas can be used to probe development\, function and dysfunction in new ways: (1) Profiling embryonic retinal ganglion cells (RGCs) to learn how they diversify into ~45 types. (2) Analyzing RGC types following damage to demonstrate dramatic differences in their resilience to injury and identify genes that contribute to resilience. (3) Generating primate retinal atlases and using them to assess expression of genes implicated in blinding diseases. (4) Probing the evolution of cell types by profiling cells from many vertebrate species. \nRegister in advance for this webinar: https://mit.zoom.us/webinar/register/WN_pwTd05G6RlWhwXgMMFhv1w
URL:https://scienceinboston.com/event/joshua-sanes-cell-types-as-building-blocks-of-neural-circuits/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210405T160000
DTEND;TZID=America/New_York:20210405T170000
DTSTAMP:20260414T034911
CREATED:20210325T165855Z
LAST-MODIFIED:20210325T165855Z
UID:27684-1617638400-1617642000@scienceinboston.com
SUMMARY:Joshua Sanes | Cell Types as Building Blocks of Neural Circuits
DESCRIPTION:Join us for the 2021 Edward M. Scolnick Prize in Neuroscience Lecture \nCell Types as Building Blocks of Neural Circuits \nJoshua Sanes\, Harvard University \nAbstract: Classification of neurons was a major preoccupation of Cajal\, but later came to be viewed as a fairly boring enterprise. Over the past few decades\, however\, inability to define neuronal types emerged as a major bottleneck in analysis of neural circuits and brain disorders. The introduction of high throughput single cell RNAseq in 2015 provided a new way to approach this problem. I will describe its use to generate an atlas of 130 cell types from mouse retina\, a particularly accessible part of the brain\, and then show how the atlas can be used to probe development\, function and dysfunction in new ways: (1) Profiling embryonic retinal ganglion cells (RGCs) to learn how they diversify into ~45 types. (2) Analyzing RGC types following damage to demonstrate dramatic differences in their resilience to injury and identify genes that contribute to resilience. (3) Generating primate retinal atlases and using them to assess expression of genes implicated in blinding diseases. (4) Probing the evolution of cell types by profiling cells from many vertebrate species. \nRegister in advance for this webinar: https://mit.zoom.us/webinar/register/WN_pwTd05G6RlWhwXgMMFhv1w
URL:https://scienceinboston.com/event/joshua-sanes-cell-types-as-building-blocks-of-neural-circuits-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210406T160000
DTEND;TZID=America/New_York:20210406T170000
DTSTAMP:20260414T034911
CREATED:20210325T165729Z
LAST-MODIFIED:20210325T165729Z
UID:13560-1617724800-1617728400@scienceinboston.com
SUMMARY:Biology Colloquium Series (Dr. Dianne Newman)
DESCRIPTION:Speaker: Dr. Dianne K. Newman\, California Institute of Technology\, hosted by the Chipperfield Graduate Committee. Title: “Context matters: the agathokakological roles of redox-active “antibiotics”. The Biology Colloquium is a weekly seminar held throughout the academic year\, featuring distinguished speakers in many areas of the biological sciences\, from universities and institutions worldwide. More information on speakers\, their affiliations\, and titles of their talks will be added as available. The Colloquium will zoom at 4:00PM  Tuesdays during the school year. Contact: Linda Earle lkn@mit.edu \n 
URL:https://scienceinboston.com/event/biology-colloquium-series-dr-dianne-newman/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210406T160000
DTEND;TZID=America/New_York:20210406T170000
DTSTAMP:20260414T034911
CREATED:20210325T165729Z
LAST-MODIFIED:20210325T165729Z
UID:27683-1617724800-1617728400@scienceinboston.com
SUMMARY:Biology Colloquium Series (Dr. Dianne Newman)
DESCRIPTION:Speaker: Dr. Dianne K. Newman\, California Institute of Technology\, hosted by the Chipperfield Graduate Committee. Title: “Context matters: the agathokakological roles of redox-active “antibiotics”. The Biology Colloquium is a weekly seminar held throughout the academic year\, featuring distinguished speakers in many areas of the biological sciences\, from universities and institutions worldwide. More information on speakers\, their affiliations\, and titles of their talks will be added as available. The Colloquium will zoom at 4:00PM  Tuesdays during the school year. Contact: Linda Earle lkn@mit.edu \n 
URL:https://scienceinboston.com/event/biology-colloquium-series-dr-dianne-newman-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210406T170000
DTEND;TZID=America/New_York:20210406T180000
DTSTAMP:20260414T034911
CREATED:20210324T231701Z
LAST-MODIFIED:20210324T231732Z
UID:13546-1617728400-1617732000@scienceinboston.com
SUMMARY:Science for All Seasons - Proteomics: Translating the Code of Life
DESCRIPTION:The genome encodes the basic blueprints and switches underlying everything a cell does\, but it’s the proteome — the cell’s collection of proteins — that does the work of carrying signals\, turning circuits on and off\, processing energy\, and more. How do researchers study the proteome\, and how does that knowledge translate into new approaches to treating disease? Research scientist Namrata Udeshi and physician-scientist Michael Gillette will take us on a tour of the proteome and some of the opportunities that the science of proteomics presents for advancing human health.
URL:https://scienceinboston.com/event/science-for-all-seasons-proteomics-translating-the-code-of-life/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210406T170000
DTEND;TZID=America/New_York:20210406T180000
DTSTAMP:20260414T034911
CREATED:20210324T231701Z
LAST-MODIFIED:20210324T231701Z
UID:27680-1617728400-1617732000@scienceinboston.com
SUMMARY:Science for All Seasons - Proteomics: Translating the Code of Life
DESCRIPTION:The genome encodes the basic blueprints and switches underlying everything a cell does\, but it’s the proteome — the cell’s collection of proteins — that does the work of carrying signals\, turning circuits on and off\, processing energy\, and more. How do researchers study the proteome\, and how does that knowledge translate into new approaches to treating disease? Research scientist Namrata Udeshi and physician-scientist Michael Gillette will take us on a tour of the proteome and some of the opportunities that the science of proteomics presents for advancing human health.
URL:https://scienceinboston.com/event/science-for-all-seasons-proteomics-translating-the-code-of-life-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20210408T130000
DTEND;TZID=America/Vancouver:20210408T140000
DTSTAMP:20260414T034911
CREATED:20210317T173417Z
LAST-MODIFIED:20210401T195311Z
UID:13405-1617886800-1617890400@scienceinboston.com
SUMMARY:Seeing the Whole Blueprint: Uncovering the Purpose of “Genomic Junk”
DESCRIPTION:Today\, scientists know far more about the human genome—the blueprint of our lives— than was ever imagined when the Human Genome Project was undertaken in the 1990s. And we have entered an era where efficient gene editing is possible. Yet\, we still lack a clear understanding of how the full genome works. We don’t know the function served by many of our genes; nor do we know the genes underlying many diseases. \nWhitehead Institute Member Yukiko Yamashita postulates one reason we lack these key pieces of knowledge: there are many biological processes and phenomena that we do not even know exist\, making it impossible to assign a gene’s function to them. \nIn this webinar\, Yamashita will highlight ways in which fundamental research brings novel biological processes to light. And she will introduce her lab’s latest discoveries on the function of satellite DNA\, which has long been regarded as “genomic junk.”
URL:https://scienceinboston.com/event/seeing-the-whole-blueprint-uncovering-the-purpose-of-genomic-junk/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Vancouver:20210408T130000
DTEND;TZID=America/Vancouver:20210408T140000
DTSTAMP:20260414T034911
CREATED:20210317T173417Z
LAST-MODIFIED:20210317T173417Z
UID:27673-1617886800-1617890400@scienceinboston.com
SUMMARY:Seeing the Whole Blueprint: Uncovering the Purpose of “Genomic Junk”
DESCRIPTION:Today\, scientists know far more about the human genome—the blueprint of our lives— than was ever imagined when the Human Genome Project was undertaken in the 1990s. And we have entered an era where efficient gene editing is possible. Yet\, we still lack a clear understanding of how the full genome works. We don’t know the function served by many of our genes; nor do we know the genes underlying many diseases. \nWhitehead Institute Member Yukiko Yamashita postulates one reason we lack these key pieces of knowledge: there are many biological processes and phenomena that we do not even know exist\, making it impossible to assign a gene’s function to them. \nIn this webinar\, Yamashita will highlight ways in which fundamental research brings novel biological processes to light. And she will introduce her lab’s latest discoveries on the function of satellite DNA\, which has long been regarded as “genomic junk.”
URL:https://scienceinboston.com/event/seeing-the-whole-blueprint-uncovering-the-purpose-of-genomic-junk-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210408T153000
DTEND;TZID=America/New_York:20210408T170000
DTSTAMP:20260414T034911
CREATED:20210401T182936Z
LAST-MODIFIED:20210401T182936Z
UID:13668-1617895800-1617901200@scienceinboston.com
SUMMARY:OEB Seminar Series: Patricia Wittkopp
DESCRIPTION:Genetic links between pigmentation and mating behavior in Drosophila \nAbstract: Pigmentation and mating behavior are some of the most variable traits among Drosophila species\, often showing correlated changes that suggest they might be co-evolving. Such co-evolution can occur because of correlated selection pressures\, genetic linkage between loci affecting different traits\, or effects of a single gene on multiple traits (pleiotropy). Distinguishing among these causes requires identifying the genetic basis of variation in both traits. In this seminar\, I will discuss genetic changes contributing differences in body color\, cuticular hydrocarbons (some of which act as pheromones)\, and behaviors such as wing extension and mounting that affect mating success. These data provide evidence for both linkage and pleiotropy contributing to the co-occurrence of these divergent traits.
URL:https://scienceinboston.com/event/oeb-seminar-series-patricia-wittkopp/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210408T153000
DTEND;TZID=America/New_York:20210408T170000
DTSTAMP:20260414T034911
CREATED:20210401T182936Z
LAST-MODIFIED:20210401T182936Z
UID:27686-1617895800-1617901200@scienceinboston.com
SUMMARY:OEB Seminar Series: Patricia Wittkopp
DESCRIPTION:Genetic links between pigmentation and mating behavior in Drosophila \nAbstract: Pigmentation and mating behavior are some of the most variable traits among Drosophila species\, often showing correlated changes that suggest they might be co-evolving. Such co-evolution can occur because of correlated selection pressures\, genetic linkage between loci affecting different traits\, or effects of a single gene on multiple traits (pleiotropy). Distinguishing among these causes requires identifying the genetic basis of variation in both traits. In this seminar\, I will discuss genetic changes contributing differences in body color\, cuticular hydrocarbons (some of which act as pheromones)\, and behaviors such as wing extension and mounting that affect mating success. These data provide evidence for both linkage and pleiotropy contributing to the co-occurrence of these divergent traits.
URL:https://scienceinboston.com/event/oeb-seminar-series-patricia-wittkopp-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210414T180000
DTEND;TZID=America/New_York:20210414T190000
DTSTAMP:20260414T034911
CREATED:20210401T183257Z
LAST-MODIFIED:20210408T210222Z
UID:13671-1618423200-1618426800@scienceinboston.com
SUMMARY:Free Virtual Lecture - Body Builders: How Animals Regenerate New Parts
DESCRIPTION:Regeneration is a remarkable phenomenon in which an animal can regrow parts of its body that are lost or damaged by injury. Humans\, for example\, can repair some organs\, but some animals can rebuild their entire bodies from small pieces of tissue. How do these animals accomplish this feat? And why is it that humans cannot regenerate as well as these animals can? Studies of how regeneration works at the molecular and cellular level are beginning to answer the first question. To answer the second question\, we have to understand how regeneration has evolved. Mansi Srivastava will highlight major insights about regeneration based on her team’s research on the three- banded panther worm\, a marine invertebrate species that enables us to study how regeneration works and how the process has evolved. \nMansi Srivastava\, John L. Loeb Associate Professor of the Natural Sciences; Curator of Invertebrate Zoology\, Organismic and Evolutionary Biology\, Museum of Comparative Zoology\, Harvard University \nEvolution Matters Lecture Series\nSeries supported by a generous gift from Drs. Herman and Joan Suit \nPresented by the Harvard Museum of Natural History and the Harvard Museums of Science & Culture \nMansi Srivastava photo by Tim Bradbury. Other image courtesy Mansi Srivastava.
URL:https://scienceinboston.com/event/free-virtual-lecture-body-builders-how-animals-regenerate-new-parts/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210414T180000
DTEND;TZID=America/New_York:20210414T190000
DTSTAMP:20260414T034911
CREATED:20210401T183257Z
LAST-MODIFIED:20210401T183257Z
UID:27687-1618423200-1618426800@scienceinboston.com
SUMMARY:Free Virtual Lecture - Body Builders: How Animals Regenerate New Parts
DESCRIPTION:Regeneration is a remarkable phenomenon in which an animal can regrow parts of its body that are lost or damaged by injury. Humans\, for example\, can repair some organs\, but some animals can rebuild their entire bodies from small pieces of tissue. How do these animals accomplish this feat? And why is it that humans cannot regenerate as well as these animals can? Studies of how regeneration works at the molecular and cellular level are beginning to answer the first question. To answer the second question\, we have to understand how regeneration has evolved. Mansi Srivastava will highlight major insights about regeneration based on her team’s research on the three- banded panther worm\, a marine invertebrate species that enables us to study how regeneration works and how the process has evolved. \nMansi Srivastava\, John L. Loeb Associate Professor of the Natural Sciences; Curator of Invertebrate Zoology\, Organismic and Evolutionary Biology\, Museum of Comparative Zoology\, Harvard University \nEvolution Matters Lecture Series\nSeries supported by a generous gift from Drs. Herman and Joan Suit \nPresented by the Harvard Museum of Natural History and the Harvard Museums of Science & Culture \nMansi Srivastava photo by Tim Bradbury. Other image courtesy Mansi Srivastava.
URL:https://scienceinboston.com/event/free-virtual-lecture-body-builders-how-animals-regenerate-new-parts-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210415T160000
DTEND;TZID=America/New_York:20210415T170000
DTSTAMP:20260414T034911
CREATED:20210405T163204Z
LAST-MODIFIED:20210412T024520Z
UID:13794-1618502400-1618506000@scienceinboston.com
SUMMARY:Exploring the Molecular and Neural Circuit Architecture of Goal-Directed Behavior
DESCRIPTION:Join us for a colloquium presented by Marc Fuccillo\, UPenn Medical School. \nTitle: Exploring the molecular and neural circuit architecture of goal-directed behavior \nAbstract:  The organization of animal behavior according to goals is a key determinant of overall fitness and the product of interrelated behavioral processes – attention to relevant environmental cues\, outcome-based choice reinforcement and avoidance\, as well as invigoration of motor performance. Disruption in any of these processes can produce goal-directed dysfunction\, a key behavioral endophenotype observed across neuropsychiatric disorders. My lab is interested in how specific neural circuits support these behavioral processes\, in particular the interactions between afferent cortical projections and local striatal circuitry. In addition\, we ask how disease-associated molecular disruptions alter these networks\, leading to the development of dysregulated reward-based motor control. In this talk\, I discuss three ongoing projects: 1. a local striatal inhibitory population that modulates goal-directed learning and local dopamine signaling; 2. divergent functional coding of goal-directed behavior by prefrontal projections targeting distinct striatal compartments\, and 3. the contributions of Neurexin1\, a synaptic adhesion molecule widely implicated in brain disease\, to alterations in value-based decision-making.
URL:https://scienceinboston.com/event/exploring-the-molecular-and-neural-circuit-architecture-of-goal-directed-behavior/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210415T160000
DTEND;TZID=America/New_York:20210415T170000
DTSTAMP:20260414T034911
CREATED:20210405T163204Z
LAST-MODIFIED:20210405T163204Z
UID:27693-1618502400-1618506000@scienceinboston.com
SUMMARY:Exploring the Molecular and Neural Circuit Architecture of Goal-Directed Behavior
DESCRIPTION:Join us for a colloquium presented by Marc Fuccillo\, UPenn Medical School. \nTitle: Exploring the molecular and neural circuit architecture of goal-directed behavior \nAbstract:  The organization of animal behavior according to goals is a key determinant of overall fitness and the product of interrelated behavioral processes – attention to relevant environmental cues\, outcome-based choice reinforcement and avoidance\, as well as invigoration of motor performance. Disruption in any of these processes can produce goal-directed dysfunction\, a key behavioral endophenotype observed across neuropsychiatric disorders. My lab is interested in how specific neural circuits support these behavioral processes\, in particular the interactions between afferent cortical projections and local striatal circuitry. In addition\, we ask how disease-associated molecular disruptions alter these networks\, leading to the development of dysregulated reward-based motor control. In this talk\, I discuss three ongoing projects: 1. a local striatal inhibitory population that modulates goal-directed learning and local dopamine signaling; 2. divergent functional coding of goal-directed behavior by prefrontal projections targeting distinct striatal compartments\, and 3. the contributions of Neurexin1\, a synaptic adhesion molecule widely implicated in brain disease\, to alterations in value-based decision-making.
URL:https://scienceinboston.com/event/exploring-the-molecular-and-neural-circuit-architecture-of-goal-directed-behavior-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210422T153000
DTEND;TZID=America/New_York:20210422T170000
DTSTAMP:20260414T034911
CREATED:20210401T183909Z
LAST-MODIFIED:20210412T190551Z
UID:13675-1619105400-1619110800@scienceinboston.com
SUMMARY:OEB Seminar Series: Marie Dacke
DESCRIPTION:As the crow flies and the beetle rolls: Straight-line orientation from behavior to neurons \nAbstract: The seemingly simple act of walking in a straight line involves a complex interplay of various sensory modalities\, the motor system\, and cognition. This is obvious to anyone who have ever found themselves lost in the desert at night\, or in a forest when the sun is high in the sky. A dung beetle released in the same unchartered territory does not move in circles\, but holds a chosen bearing until it encounters a suitable spot to bury its ball of dung. The key to the beetle’s success lies in their ability to detect and orient via a large repertoire of celestial compass cues\, from the bright sun to the weak intensity differences of light provided by the Milky Way. \nA beetle’s drive to adhere to its set course is so strong that it sticks to it regardless of the costs; over stones\, through bushes and grass or in an experimental arena. However\, if a beetle is forced to make a new ball\, the bearing information is reset in its brain and a new course is set. This unique and robust orientation behaviour\, in combination with an accessible brain\, make the dung beetle an ideal model system for understanding the fundamental visual and neural processes underlying straight-line orientation. \nThe presentation provides an overview of recent behavioural\, anatomical and physiological results concerning how an insect brain is designed to facilitate straight-line orientation. \nRegister here: https://harvard.zoom.us/webinar/register/WN_Xh4J3vjLQyGTlOC30jvZeA
URL:https://scienceinboston.com/event/oeb-seminar-series-marie-dacke/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210422T153000
DTEND;TZID=America/New_York:20210422T170000
DTSTAMP:20260414T034911
CREATED:20210401T183909Z
LAST-MODIFIED:20210401T183909Z
UID:27688-1619105400-1619110800@scienceinboston.com
SUMMARY:OEB Seminar Series: Marie Dacke
DESCRIPTION:As the crow flies and the beetle rolls: Straight-line orientation from behavior to neurons \nAbstract: The seemingly simple act of walking in a straight line involves a complex interplay of various sensory modalities\, the motor system\, and cognition. This is obvious to anyone who have ever found themselves lost in the desert at night\, or in a forest when the sun is high in the sky. A dung beetle released in the same unchartered territory does not move in circles\, but holds a chosen bearing until it encounters a suitable spot to bury its ball of dung. The key to the beetle’s success lies in their ability to detect and orient via a large repertoire of celestial compass cues\, from the bright sun to the weak intensity differences of light provided by the Milky Way. \nA beetle’s drive to adhere to its set course is so strong that it sticks to it regardless of the costs; over stones\, through bushes and grass or in an experimental arena. However\, if a beetle is forced to make a new ball\, the bearing information is reset in its brain and a new course is set. This unique and robust orientation behaviour\, in combination with an accessible brain\, make the dung beetle an ideal model system for understanding the fundamental visual and neural processes underlying straight-line orientation. \nThe presentation provides an overview of recent behavioural\, anatomical and physiological results concerning how an insect brain is designed to facilitate straight-line orientation. \nRegister here: https://harvard.zoom.us/webinar/register/WN_Xh4J3vjLQyGTlOC30jvZeA
URL:https://scienceinboston.com/event/oeb-seminar-series-marie-dacke-2/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210422T160000
DTEND;TZID=America/New_York:20210422T170000
DTSTAMP:20260414T034911
CREATED:20210401T195803Z
LAST-MODIFIED:20210419T160938Z
UID:13698-1619107200-1619110800@scienceinboston.com
SUMMARY:Colloquium on Brain and Cognition with Dr. Mathew Diamond
DESCRIPTION:TITLE: \nNeuronal algorithms for extracting multiple percepts from a single stimulus \nABSTRACT: \nWhen we consider the processing of a tactile stimulus\, it is natural to focus on what the stimulus feels like and how the perceived features are encoded by neurons. But a second percept\, explicitly or implicitly\, accompanies the tactile experience – the feeling of time occupied by that stimulus. To explore the connection between stimulus perception and time perception\, we begin with human and rat psychophysics. When subjects judge the duration of a vibration applied to the fingertip (human) or whiskers (rat)\, increasing stimulus intensity leads to increasing perceived duration. Symmetrically\, increasing vibration duration leads to increasing perceived intensity. From this relationship\, we build a computational framework where the vibration-evoked firing early in the processing stream is accumulated by two integrators\, in parallel\, each integrator giving rise to a corresponding percept (intensity and duration). This framework makes predictions for the perceptual effects – on both intensity and duration – of direct manipulation of firing in sensory cortex\, which we verify by optogenetics in rats. However\, just when everything begins to make sense\, the story becomes more complex: a subtle change in the physical features of the tactile stimulus causes the engagement of a very different pathway for the perception of time. We conclude that the mechanisms underlying the feeling of stimulus duration are multiple and are adaptable to stimulus properties.
URL:https://scienceinboston.com/event/colloquium-on-brain-and-cognition-with-mathew-diamond-phd/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210422T160000
DTEND;TZID=America/New_York:20210422T170000
DTSTAMP:20260414T034911
CREATED:20210401T195803Z
LAST-MODIFIED:20210401T195803Z
UID:27691-1619107200-1619110800@scienceinboston.com
SUMMARY:Colloquium on Brain and Cognition with Dr. Mathew Diamond
DESCRIPTION:TITLE: \nNeuronal algorithms for extracting multiple percepts from a single stimulus \nABSTRACT: \nWhen we consider the processing of a tactile stimulus\, it is natural to focus on what the stimulus feels like and how the perceived features are encoded by neurons. But a second percept\, explicitly or implicitly\, accompanies the tactile experience – the feeling of time occupied by that stimulus. To explore the connection between stimulus perception and time perception\, we begin with human and rat psychophysics. When subjects judge the duration of a vibration applied to the fingertip (human) or whiskers (rat)\, increasing stimulus intensity leads to increasing perceived duration. Symmetrically\, increasing vibration duration leads to increasing perceived intensity. From this relationship\, we build a computational framework where the vibration-evoked firing early in the processing stream is accumulated by two integrators\, in parallel\, each integrator giving rise to a corresponding percept (intensity and duration). This framework makes predictions for the perceptual effects – on both intensity and duration – of direct manipulation of firing in sensory cortex\, which we verify by optogenetics in rats. However\, just when everything begins to make sense\, the story becomes more complex: a subtle change in the physical features of the tactile stimulus causes the engagement of a very different pathway for the perception of time. We conclude that the mechanisms underlying the feeling of stimulus duration are multiple and are adaptable to stimulus properties.
URL:https://scienceinboston.com/event/colloquium-on-brain-and-cognition-with-mathew-diamond-phd-2/
LOCATION:Online
END:VEVENT
END:VCALENDAR