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DTSTART;TZID=America/New_York:20190919T120000
DTEND;TZID=America/New_York:20190919T160000
DTSTAMP:20190903T191044Z
CREATED:20190903T191044Z
LAST-MODIFIED:20190903T191044Z
UID:6373-1568894400-1568908800@scienceinboston.com
SUMMARY:Fall Career Fair
DESCRIPTION:The WPI Fall Career Fair will be held on September 19\, 2019\, 12pm-4pm and is open to students and alumni of all degrees and disciplines and is ideal for employers looking to fill full-time\, internship\, and co-op positions.
URL:https://scienceinboston.com/event/fall-career-fair/
LOCATION:WPI – Sports & Rec Center\, 100 Institute Rd\, Worcester\, MA\, 01609\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190919T120000
DTEND;TZID=America/New_York:20190919T160000
DTSTAMP:20190903T191044Z
CREATED:20190903T191044Z
LAST-MODIFIED:20190903T191044Z
UID:27325-1568894400-1568908800@scienceinboston.com
SUMMARY:Fall Career Fair
DESCRIPTION:The WPI Fall Career Fair will be held on September 19\, 2019\, 12pm-4pm and is open to students and alumni of all degrees and disciplines and is ideal for employers looking to fill full-time\, internship\, and co-op positions.
URL:https://scienceinboston.com/event/fall-career-fair-2/
LOCATION:WPI – Sports & Rec Center\, 100 Institute Rd\, Worcester\, MA\, 01609\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190919T083000
DTEND;TZID=America/New_York:20190919T183000
DTSTAMP:20190816T143852Z
CREATED:20190816T143852Z
LAST-MODIFIED:20190816T143852Z
UID:6215-1568881800-1568917800@scienceinboston.com
SUMMARY:Third Annual "Chemical Biology in The HUB" Symposium
DESCRIPTION:This third-in-a-series of scientific talks will focus on cutting edge research in Chemical Biology from both academic and industry labs in the areas of translational chemical biology\, machine learning\, novel target identification and validation\, chemical imaging\, as well as new chemical modalities. \nThis day-long symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees. \nWe wish to thank all of the sponsors and volunteers from industry who are making this possible. Our sponsors include\, in alphabetical order\, The American Chemical Society\, ACS Chemical Biology\, ACS Central Science\, Arrakis Therapeutics\, AstraZeneca\, Biogen\, C4 Therapeutics\, Celgene\, Jnana Therapeutics\, Millipore Sigma\, New England BioLabs\, Northeastern Section of the ACS\, Novartis\, Pfizer\, Sanofi\, Vertex. Our organizers are pleased to continue this fall tradition this year and in the coming years; please be in contact with us (below) if you are interested in participating in future symposia through volunteering\, through sponsorship\, or other means. \nRegistration is required and a ticket will be necessary for admission to the symposium and the networking reception. There are several parking lots located in the area close to Merck. \nRegistration or other questions? Please contact: Andrew Scholte\, Chair of NESACS\, ascholte@gmail.com\n \n\nSchedule of Events (Stay Tuned for Detailed Schedule)\n \n8:30 – 9:00 AM Registration and Breakfast\n \n9:00 AM – 12:20 PM Program \n12:20 PM – 1:30 PM Lunch and Poster Session\n \n1:30 PM – 5:00 PM Program\n \n5:00 PM – 6:30 PM Reception and Poster Session \n\nQuestions? Please contact: Andrew Scholte\, ascholte@gmail.com. \nTHE PUBLIC IS INVITED – RESERVATIONS ARE REQUIRED \n\nFAQs \nWhat are my transport/parking options getting to the event? \nMerck Research Laboratories is located in the Longwood Medical Area and is walking distance from the D-line (Fenway Stop) and E-line (Museum of Fine Arts) of the Green Line. There are also numerous parking garages in the area.  \nPlease contact the organizers regarding carpooling and other options. \nFor driving directions from where you will begin your trip\, enter “33 Avenue Louis Pasteur\, Boston\, MA 02115\,” \nWhere can I contact the organizer with any questions? \nWith any questions whatsoever\, please contact Andrew Scholte\, ascholte@gmail.com \nIs my registration/ticket transferrable? \nYes\, please contact Andrew Scholte before September 12\, 2019.
URL:https://scienceinboston.com/event/third-annual-chemical-biology-in-the-hub-symposium/
LOCATION:Merck Research Laboratories\, 33 Avenue Louis Pasteur\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190919T083000
DTEND;TZID=America/New_York:20190919T183000
DTSTAMP:20190816T143852Z
CREATED:20190816T143852Z
LAST-MODIFIED:20190816T143852Z
UID:27318-1568881800-1568917800@scienceinboston.com
SUMMARY:Third Annual "Chemical Biology in The HUB" Symposium
DESCRIPTION:This third-in-a-series of scientific talks will focus on cutting edge research in Chemical Biology from both academic and industry labs in the areas of translational chemical biology\, machine learning\, novel target identification and validation\, chemical imaging\, as well as new chemical modalities. \nThis day-long symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees. \nWe wish to thank all of the sponsors and volunteers from industry who are making this possible. Our sponsors include\, in alphabetical order\, The American Chemical Society\, ACS Chemical Biology\, ACS Central Science\, Arrakis Therapeutics\, AstraZeneca\, Biogen\, C4 Therapeutics\, Celgene\, Jnana Therapeutics\, Millipore Sigma\, New England BioLabs\, Northeastern Section of the ACS\, Novartis\, Pfizer\, Sanofi\, Vertex. Our organizers are pleased to continue this fall tradition this year and in the coming years; please be in contact with us (below) if you are interested in participating in future symposia through volunteering\, through sponsorship\, or other means. \nRegistration is required and a ticket will be necessary for admission to the symposium and the networking reception. There are several parking lots located in the area close to Merck. \nRegistration or other questions? Please contact: Andrew Scholte\, Chair of NESACS\, ascholte@gmail.com\n \n\nSchedule of Events (Stay Tuned for Detailed Schedule)\n \n8:30 – 9:00 AM Registration and Breakfast\n \n9:00 AM – 12:20 PM Program \n12:20 PM – 1:30 PM Lunch and Poster Session\n \n1:30 PM – 5:00 PM Program\n \n5:00 PM – 6:30 PM Reception and Poster Session \n\nQuestions? Please contact: Andrew Scholte\, ascholte@gmail.com. \nTHE PUBLIC IS INVITED – RESERVATIONS ARE REQUIRED \n\nFAQs \nWhat are my transport/parking options getting to the event? \nMerck Research Laboratories is located in the Longwood Medical Area and is walking distance from the D-line (Fenway Stop) and E-line (Museum of Fine Arts) of the Green Line. There are also numerous parking garages in the area.  \nPlease contact the organizers regarding carpooling and other options. \nFor driving directions from where you will begin your trip\, enter “33 Avenue Louis Pasteur\, Boston\, MA 02115\,” \nWhere can I contact the organizer with any questions? \nWith any questions whatsoever\, please contact Andrew Scholte\, ascholte@gmail.com \nIs my registration/ticket transferrable? \nYes\, please contact Andrew Scholte before September 12\, 2019.
URL:https://scienceinboston.com/event/third-annual-chemical-biology-in-the-hub-symposium-2/
LOCATION:Merck Research Laboratories\, 33 Avenue Louis Pasteur\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190917T100000
DTEND;TZID=America/New_York:20190917T150000
DTSTAMP:20190909T144114Z
CREATED:20190909T144114Z
LAST-MODIFIED:20190909T144114Z
UID:6429-1568714400-1568732400@scienceinboston.com
SUMMARY:Mass Cytometry Day
DESCRIPTION:You are invited to Mass Cytometry Day in Boston. Let’s talk about why #heavymetalsrock\n\n\n\n\n\n\nAbout this Event\n\n\nSeminar Talks—Five speakers will share insights\, research\, and results. \nLuncheon—Mingle with other researchers from the surrounding area. \nStep-Right-Up Q&A Table—Discuss your current projects and future ideas with an application scientist. Brand new to Mass Cytometry or Imaging Mass Cytometry? This is the perfect place to start. \nProgram\nContinental Breakfast \ncranberry scones\, miniature banana muffins\, lemon blueberry tea bread \nbottled water\, regular and decaf Starbucks coffee\, assorted Tazo tea \nExecutive Welcome:\nJonathan Day\, VP Commercial Operations\, Fluidigm Corporation \nSpeaker 1: Cynthia Guidos\, PhD\nSenior Scientist\, Developmental and Stem Cell Biology Program\, Hospital for Sick Children Research Institute in Toronto\, ON\, Canada; Professor of Immunology\, Faculty of Medicine\, University of Toronto \n“High Dimensional Characterization of Immune Cells in Normal and Diseased Micro-environments “ \nAbstract : Dissecting disease-driving immune responses presents a major analytical challenge because they are generally mediated by concomitant effects of diverse immune cell lineages\, which are highly dynamic and heterogeneous at both the individual and the population levels. Thus\, highly dimensional single cell and systems-wide approaches are needed to comprehensively characterize the immune cells in health and disease. Helios mass cytometers can measure expression of up to 48 different markers per cell\, making CyTOF the leading technology for discovering biomarkers of immune-mediated diseases. In her presentation\, Dr. Guidos will discuss how she is using mass cytometry to deeply characterize complex cellular immune networks that underlie anti-cancer immune responses and autoimmune diseases. She will describe how her group uses clustering\, machine learning and dimensionality reduction algorithms to automatically identify and visualize differences in subset distribution and functional states across samples in an unbiased fashion. Finally\, Dr. Guidos will overview her use of Fluidigm’s Hyperion multi-plexed imaging mass cytometry platform to enable deep characterization of immune cells within normal and diseased tissue microenvironments. \nSpeaker 2: Emily Thrash\, PhD\nScientist II \, Center for Immuno-Oncology – Immune Assessment Laboratory\, Dana-Farber Cancer Institute \n“Application of high-throughput mass cytometry to phenotype adaptive and innate immune subsets for clinical trials” \nBiomarker discovery in clinical research is currently limited by the inherent complexity of cancer and immune responses in patients\, as well as a lack of validated multi-parameter immuno-phenotyping methodology for large-scale trials. With more measurable parameters than traditional flow cytometry\, mass cytometry (CyTOF) is poised to identify outcome-associated cellular signatures\, follow disease progression and predict therapeutic responses. However\, in a clinical setting\, with large sample numbers collected at different timepoints\, reduction of technical variability is critical. Using healthy donor PBMCs\, we present the design and validation of two CyTOF panels focused on adaptive or innate immune response. Reference sample spike-in decreases batch effects between experiments and we demonstrate high-throughput sample number capabilities. Here we present our workflow and development for robustly immune-phenotyping clinical samples with CyTOF. \nSpeaker 3: Andrew Larry Frelinger\, PhD\nAssistant Professor of Pediatrics\, Harvard Medical School\, Associate Director\, Center for Platelet Research Studies\,Research Associate in Medicine\, Division of Hematology/Oncology\, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center Boston Children’s Hospital/Dana-Farber Cancer Institute \nLunch\nTraditional Sandwich Buffet \nassorted traditional sandwiches: roasted turkey\, roast beef\, smoked ham\, tuna salad\, chicken salad\, tomato\, basil\, mozzarella \nFLIK chips\, hand fruit \nhouse baked FLIK signature chocolate chip cookies \nbottled water\, soda \nSpeaker 4: Douglas Linn\, PhD\nAssociate Principal Scientist\, Merck & Co.\, Inc. \n“Imaging mass cytometry (IMC) as a powerful tool for immunophenotyping human and mouse tissues” \nAbstract: The recent advent of imaging mass cytometry (IMC) applies the technologies of CyTOF to tissue imaging\, building upon key weaknesses of flow cytometry and multiplex immunohistochemistry to establish a powerful tool for examining cellular interactions within complex microenvironments like tumors. We set out to establish and validate IMC capabilities within MRL Boston by analyzing tumors and lymphoid tissue stained with panels of human or mouse markers. Tissue processing and staining protocols were optimized to achieve simultaneous staining of dozens of immune markers\, thus identifying major lymphocyte and myeloid subsets. Unsupervised clustering algorithms allowed examination of expression at population levels or single cell resolution. Together these efforts have validated the use of IMC to profile tumor and lymphoid tissues using large panels of immune markers. The highly multiplexed results that can be obtained will serve an important complementary role in immunophenotyping to explore biology and understand mechanism of action of cancer immunotherapies. \nSpeaker 5: Nikhil Singh\, MD\, PhD\nInstructor\, Section of Nephrology\, Department of Internal Medicinel\, Cantley Lab\, Yale University \n“Highly multiplexed\, spatially preserved analysis of human kidney injury with Imaging Mass Cytometry” \nAbstract: The lack of therapies for acute tubular injury (ATI) derives largely from our incomplete understanding of the biology of the injured human kidney. Although renal biopsy is commonly used in the diagnosis of acute kidney injury\, the small amount of tissue obtained has previously limited the ability to use patient samples for discovery purposes. Imaging mass cytometry (IMC) is a novel technology which permits concurrent analysis of >40 markers on a formalin-fixed tissue section\, ideal for scarce and archival samples. We have developed a highly reproducible methodology for IMC-based interrogation of the human kidney coupled to a machine-learning analysis pipeline. We have utilized this technique to perform comparative\, quantitative\, spatially preserved expression analysis of healthy and injured human tissue. With our combined imaging-analysis approach we have created a reference atlas for the adult human kidney\, defining selected intrinsic and immune cell proportions and their spatial organization in 16 histopathologically normal samples. In injured kidneys with interstitial infiltrate\, we have quantified both expected and novel changes to cellular proportions and tissue architecture. For a cohort of patients who underwent renal biopsy at two affiliated hospitals from 2011-2018 and whose biopsies showed ATI\, we are adjudicating mechanism of injury by chart review and are interrogating banked tissue by IMC to identify immune drivers and cellular responses to injury\, create a quantitative atlas of human ATI\, and elucidate potential targets for therapeutic intervention. We hypothesize that unsupervised clustering of IMC data can be used to develop pathologic signatures corresponding to injury etiology and clinical outcome in ATI.
URL:https://scienceinboston.com/event/mass-cytometry-day/
LOCATION:Merck Research Laboratories\, 33 Avenue Louis Pasteur\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190917T100000
DTEND;TZID=America/New_York:20190917T150000
DTSTAMP:20190909T144114Z
CREATED:20190909T144114Z
LAST-MODIFIED:20190909T144114Z
UID:27329-1568714400-1568732400@scienceinboston.com
SUMMARY:Mass Cytometry Day
DESCRIPTION:You are invited to Mass Cytometry Day in Boston. Let’s talk about why #heavymetalsrock\n\n\n\n\n\n\nAbout this Event\n\n\nSeminar Talks—Five speakers will share insights\, research\, and results. \nLuncheon—Mingle with other researchers from the surrounding area. \nStep-Right-Up Q&A Table—Discuss your current projects and future ideas with an application scientist. Brand new to Mass Cytometry or Imaging Mass Cytometry? This is the perfect place to start. \nProgram\nContinental Breakfast \ncranberry scones\, miniature banana muffins\, lemon blueberry tea bread \nbottled water\, regular and decaf Starbucks coffee\, assorted Tazo tea \nExecutive Welcome:\nJonathan Day\, VP Commercial Operations\, Fluidigm Corporation \nSpeaker 1: Cynthia Guidos\, PhD\nSenior Scientist\, Developmental and Stem Cell Biology Program\, Hospital for Sick Children Research Institute in Toronto\, ON\, Canada; Professor of Immunology\, Faculty of Medicine\, University of Toronto \n“High Dimensional Characterization of Immune Cells in Normal and Diseased Micro-environments “ \nAbstract : Dissecting disease-driving immune responses presents a major analytical challenge because they are generally mediated by concomitant effects of diverse immune cell lineages\, which are highly dynamic and heterogeneous at both the individual and the population levels. Thus\, highly dimensional single cell and systems-wide approaches are needed to comprehensively characterize the immune cells in health and disease. Helios mass cytometers can measure expression of up to 48 different markers per cell\, making CyTOF the leading technology for discovering biomarkers of immune-mediated diseases. In her presentation\, Dr. Guidos will discuss how she is using mass cytometry to deeply characterize complex cellular immune networks that underlie anti-cancer immune responses and autoimmune diseases. She will describe how her group uses clustering\, machine learning and dimensionality reduction algorithms to automatically identify and visualize differences in subset distribution and functional states across samples in an unbiased fashion. Finally\, Dr. Guidos will overview her use of Fluidigm’s Hyperion multi-plexed imaging mass cytometry platform to enable deep characterization of immune cells within normal and diseased tissue microenvironments. \nSpeaker 2: Emily Thrash\, PhD\nScientist II \, Center for Immuno-Oncology – Immune Assessment Laboratory\, Dana-Farber Cancer Institute \n“Application of high-throughput mass cytometry to phenotype adaptive and innate immune subsets for clinical trials” \nBiomarker discovery in clinical research is currently limited by the inherent complexity of cancer and immune responses in patients\, as well as a lack of validated multi-parameter immuno-phenotyping methodology for large-scale trials. With more measurable parameters than traditional flow cytometry\, mass cytometry (CyTOF) is poised to identify outcome-associated cellular signatures\, follow disease progression and predict therapeutic responses. However\, in a clinical setting\, with large sample numbers collected at different timepoints\, reduction of technical variability is critical. Using healthy donor PBMCs\, we present the design and validation of two CyTOF panels focused on adaptive or innate immune response. Reference sample spike-in decreases batch effects between experiments and we demonstrate high-throughput sample number capabilities. Here we present our workflow and development for robustly immune-phenotyping clinical samples with CyTOF. \nSpeaker 3: Andrew Larry Frelinger\, PhD\nAssistant Professor of Pediatrics\, Harvard Medical School\, Associate Director\, Center for Platelet Research Studies\,Research Associate in Medicine\, Division of Hematology/Oncology\, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center Boston Children’s Hospital/Dana-Farber Cancer Institute \nLunch\nTraditional Sandwich Buffet \nassorted traditional sandwiches: roasted turkey\, roast beef\, smoked ham\, tuna salad\, chicken salad\, tomato\, basil\, mozzarella \nFLIK chips\, hand fruit \nhouse baked FLIK signature chocolate chip cookies \nbottled water\, soda \nSpeaker 4: Douglas Linn\, PhD\nAssociate Principal Scientist\, Merck & Co.\, Inc. \n“Imaging mass cytometry (IMC) as a powerful tool for immunophenotyping human and mouse tissues” \nAbstract: The recent advent of imaging mass cytometry (IMC) applies the technologies of CyTOF to tissue imaging\, building upon key weaknesses of flow cytometry and multiplex immunohistochemistry to establish a powerful tool for examining cellular interactions within complex microenvironments like tumors. We set out to establish and validate IMC capabilities within MRL Boston by analyzing tumors and lymphoid tissue stained with panels of human or mouse markers. Tissue processing and staining protocols were optimized to achieve simultaneous staining of dozens of immune markers\, thus identifying major lymphocyte and myeloid subsets. Unsupervised clustering algorithms allowed examination of expression at population levels or single cell resolution. Together these efforts have validated the use of IMC to profile tumor and lymphoid tissues using large panels of immune markers. The highly multiplexed results that can be obtained will serve an important complementary role in immunophenotyping to explore biology and understand mechanism of action of cancer immunotherapies. \nSpeaker 5: Nikhil Singh\, MD\, PhD\nInstructor\, Section of Nephrology\, Department of Internal Medicinel\, Cantley Lab\, Yale University \n“Highly multiplexed\, spatially preserved analysis of human kidney injury with Imaging Mass Cytometry” \nAbstract: The lack of therapies for acute tubular injury (ATI) derives largely from our incomplete understanding of the biology of the injured human kidney. Although renal biopsy is commonly used in the diagnosis of acute kidney injury\, the small amount of tissue obtained has previously limited the ability to use patient samples for discovery purposes. Imaging mass cytometry (IMC) is a novel technology which permits concurrent analysis of >40 markers on a formalin-fixed tissue section\, ideal for scarce and archival samples. We have developed a highly reproducible methodology for IMC-based interrogation of the human kidney coupled to a machine-learning analysis pipeline. We have utilized this technique to perform comparative\, quantitative\, spatially preserved expression analysis of healthy and injured human tissue. With our combined imaging-analysis approach we have created a reference atlas for the adult human kidney\, defining selected intrinsic and immune cell proportions and their spatial organization in 16 histopathologically normal samples. In injured kidneys with interstitial infiltrate\, we have quantified both expected and novel changes to cellular proportions and tissue architecture. For a cohort of patients who underwent renal biopsy at two affiliated hospitals from 2011-2018 and whose biopsies showed ATI\, we are adjudicating mechanism of injury by chart review and are interrogating banked tissue by IMC to identify immune drivers and cellular responses to injury\, create a quantitative atlas of human ATI\, and elucidate potential targets for therapeutic intervention. We hypothesize that unsupervised clustering of IMC data can be used to develop pathologic signatures corresponding to injury etiology and clinical outcome in ATI.
URL:https://scienceinboston.com/event/mass-cytometry-day-2/
LOCATION:Merck Research Laboratories\, 33 Avenue Louis Pasteur\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190913T173000
DTEND;TZID=America/New_York:20190913T193000
DTSTAMP:20190905T173049Z
CREATED:20190905T173049Z
LAST-MODIFIED:20190905T173049Z
UID:6392-1568395800-1568403000@scienceinboston.com
SUMMARY:Science in Boston Meet and Greet
DESCRIPTION:Join us on Friday\, September 13th at Meadhall to wind down from your work week with some cold ones\, cool science\, and the opportunity to win a sweet prize! \nTime: 5:30 – 7:30 PM \nVenue: Meadhall\, 4 Cambridge Center\, 90 Broadway\, Cambridge\, MA 021424 Cambridge Center\, 90 Broadway\, Cambridge\, MA 02142
URL:https://scienceinboston.com/event/science-in-boston-meet-and-greet/
LOCATION:Meadhall\, 4 Cambridge Center\, 90 Broadway\, Cambridge\, MA\, 02142\, United States
ATTACH;FMTTYPE=image/jpeg:https://scienceinboston.com/wp-content/uploads/sites/6/2019/09/SO356CXN-Science-in-Boston-Meet-Greet-1100x628.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190913T173000
DTEND;TZID=America/New_York:20190913T193000
DTSTAMP:20190905T173049Z
CREATED:20190905T173049Z
LAST-MODIFIED:20190905T173049Z
UID:27326-1568395800-1568403000@scienceinboston.com
SUMMARY:Science in Boston Meet and Greet
DESCRIPTION:Join us on Friday\, September 13th at Meadhall to wind down from your work week with some cold ones\, cool science\, and the opportunity to win a sweet prize! \nTime: 5:30 – 7:30 PM \nVenue: Meadhall\, 4 Cambridge Center\, 90 Broadway\, Cambridge\, MA 021424 Cambridge Center\, 90 Broadway\, Cambridge\, MA 02142
URL:https://scienceinboston.com/event/science-in-boston-meet-and-greet-2/
LOCATION:Meadhall\, 4 Cambridge Center\, 90 Broadway\, Cambridge\, MA\, 02142\, United States
ATTACH;FMTTYPE=image/jpeg:https://scienceinboston.com/wp-content/uploads/sites/6/2019/09/SO356CXN-Science-in-Boston-Meet-Greet-1100x628.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190912T143000
DTEND;TZID=America/New_York:20190912T173000
DTSTAMP:20190816T151708Z
CREATED:20190816T151708Z
LAST-MODIFIED:20190816T151708Z
UID:6223-1568298600-1568309400@scienceinboston.com
SUMMARY:FRAXA Biotech Games
DESCRIPTION:FRAXA Biotech Games™ raise money for research while giving members of the Boston biotech community the opportunity to meet each other and network in a friendly setting to share camaraderie\, experiences and expertise which then strengthens the Boston scientific ecosystem. \nProceeds of the event support FRAXA Research Foundation\, which funds Fragile X research in Boston area labs\, including the Mark Bear Lab at MIT’s Picower Institute and the Jeannie Lee Lab at Harvard/Mass General. FRAXA’s mission is to find effective treatments and ultimately a cure for Fragile X\, the most common inherited cause of autism and learning disabilities worldwide. \nRegistration begins at 2:30 pm. The Games start at 3:30 pm and will conclude at 5:30 pm\, immediately followed by a networking reception BBQ with food and Cash bar on The Common  from 5:30 -7:30 pm. Awards will be presented\, including awarding the Cup to the top company\, whose team achieves the highest overall score in the competition. There will be several consolation prizes as well. \nDon’t miss out! Register your team today – team slots will be filled on a first come first served basis! A team consists of 2-4 players. For more information please contact Dave Bjork at dbjorl@fraxa.org or sbeaulieu@connerstrong.com
URL:https://scienceinboston.com/event/fraxa-biotech-games/
LOCATION:The Common at Cambridge Crossing\, Cambridge\, MA\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190912T143000
DTEND;TZID=America/New_York:20190912T173000
DTSTAMP:20190816T151708Z
CREATED:20190816T151708Z
LAST-MODIFIED:20190816T151708Z
UID:27321-1568298600-1568309400@scienceinboston.com
SUMMARY:FRAXA Biotech Games
DESCRIPTION:FRAXA Biotech Games™ raise money for research while giving members of the Boston biotech community the opportunity to meet each other and network in a friendly setting to share camaraderie\, experiences and expertise which then strengthens the Boston scientific ecosystem. \nProceeds of the event support FRAXA Research Foundation\, which funds Fragile X research in Boston area labs\, including the Mark Bear Lab at MIT’s Picower Institute and the Jeannie Lee Lab at Harvard/Mass General. FRAXA’s mission is to find effective treatments and ultimately a cure for Fragile X\, the most common inherited cause of autism and learning disabilities worldwide. \nRegistration begins at 2:30 pm. The Games start at 3:30 pm and will conclude at 5:30 pm\, immediately followed by a networking reception BBQ with food and Cash bar on The Common  from 5:30 -7:30 pm. Awards will be presented\, including awarding the Cup to the top company\, whose team achieves the highest overall score in the competition. There will be several consolation prizes as well. \nDon’t miss out! Register your team today – team slots will be filled on a first come first served basis! A team consists of 2-4 players. For more information please contact Dave Bjork at dbjorl@fraxa.org or sbeaulieu@connerstrong.com
URL:https://scienceinboston.com/event/fraxa-biotech-games-2/
LOCATION:The Common at Cambridge Crossing\, Cambridge\, MA\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190911T143000
DTEND;TZID=America/New_York:20190911T174500
DTSTAMP:20190816T145733Z
CREATED:20190816T145733Z
LAST-MODIFIED:20190816T145733Z
UID:6221-1568212200-1568223900@scienceinboston.com
SUMMARY:Career Pathways for Researchers Interested in Government and Regulatory Agencies
DESCRIPTION:This panel session offers attendees an overview of the various career options available within government and regulatory agencies and provides an opportunity for participants to present questions to expert panelists. \nKeynote Speaker: \nJodi Black\, PhD\, Deputy Director of the NIH Office of Extramural Research\, NIH \nPanel Discussion and Q&A Session: \nMonica Bharel\, MD\, MPH\, Commissioner of the Massachusetts Department of Public Health \nMary Woolley\, President of Research!America\, Research!America \n  \nRegistration closes September 11. \nQuestions? Please email education@catalyst.harvard.edu.
URL:https://scienceinboston.com/event/career-pathways-for-researchers-interested-in-government-and-regulatory-agencies/
LOCATION:Harvard Medical School\, 25 Shattuck St\, Boston\, MA\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190911T143000
DTEND;TZID=America/New_York:20190911T174500
DTSTAMP:20190816T145733Z
CREATED:20190816T145733Z
LAST-MODIFIED:20190816T145733Z
UID:27320-1568212200-1568223900@scienceinboston.com
SUMMARY:Career Pathways for Researchers Interested in Government and Regulatory Agencies
DESCRIPTION:This panel session offers attendees an overview of the various career options available within government and regulatory agencies and provides an opportunity for participants to present questions to expert panelists. \nKeynote Speaker: \nJodi Black\, PhD\, Deputy Director of the NIH Office of Extramural Research\, NIH \nPanel Discussion and Q&A Session: \nMonica Bharel\, MD\, MPH\, Commissioner of the Massachusetts Department of Public Health \nMary Woolley\, President of Research!America\, Research!America \n  \nRegistration closes September 11. \nQuestions? Please email education@catalyst.harvard.edu.
URL:https://scienceinboston.com/event/career-pathways-for-researchers-interested-in-government-and-regulatory-agencies-2/
LOCATION:Harvard Medical School\, 25 Shattuck St\, Boston\, MA\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190911T080000
DTEND;TZID=America/New_York:20190912T170000
DTSTAMP:20190816T145402Z
CREATED:20190816T145402Z
LAST-MODIFIED:20190816T145402Z
UID:6218-1568188800-1568307600@scienceinboston.com
SUMMARY:NCATS Assay Guidance Workshop for High-Throughput Screening and Lead Discovery
DESCRIPTION:This free two day workshop will cover a broad range of critical concepts underlying assay development and implementation for high throughput screening (HTS) and lead discovery projects. Many of the methodologies successfully implemented in such projects have established a good deal of “tribal knowledge” within the pharmaceutical industry which is not readily found in a classroom or the literature. This tribal knowledge\, developed over decades\, has been transferred into detailed chapters within the Assay Guidance Manual to facilitate reproducible and robust assays that can identify the most promising compounds for the development of molecular probes or clinical candidates. The workshop will provide participants with a broad\, practical perspective on assay development so that they can (1) improve research projects involving drug discovery\, and know where to find further information (2) identify reagents\, methods and instrumentation that are well suited to robust assays and (3) develop robust assays and the required counter and secondary assays for targets of interest.
URL:https://scienceinboston.com/event/ncats-assay-guidance-workshop-for-high-throughput-screening-and-lead-discovery/
LOCATION:Pfizer Kendall Square\, 1 Portland Square\, Cambridge\, MA\, 02139\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190911T080000
DTEND;TZID=America/New_York:20190912T170000
DTSTAMP:20190816T145402Z
CREATED:20190816T145402Z
LAST-MODIFIED:20190816T145402Z
UID:27319-1568188800-1568307600@scienceinboston.com
SUMMARY:NCATS Assay Guidance Workshop for High-Throughput Screening and Lead Discovery
DESCRIPTION:This free two day workshop will cover a broad range of critical concepts underlying assay development and implementation for high throughput screening (HTS) and lead discovery projects. Many of the methodologies successfully implemented in such projects have established a good deal of “tribal knowledge” within the pharmaceutical industry which is not readily found in a classroom or the literature. This tribal knowledge\, developed over decades\, has been transferred into detailed chapters within the Assay Guidance Manual to facilitate reproducible and robust assays that can identify the most promising compounds for the development of molecular probes or clinical candidates. The workshop will provide participants with a broad\, practical perspective on assay development so that they can (1) improve research projects involving drug discovery\, and know where to find further information (2) identify reagents\, methods and instrumentation that are well suited to robust assays and (3) develop robust assays and the required counter and secondary assays for targets of interest.
URL:https://scienceinboston.com/event/ncats-assay-guidance-workshop-for-high-throughput-screening-and-lead-discovery-2/
LOCATION:Pfizer Kendall Square\, 1 Portland Square\, Cambridge\, MA\, 02139\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190911T080000
DTEND;TZID=America/New_York:20190911T170000
DTSTAMP:20190909T144542Z
CREATED:20190909T144542Z
LAST-MODIFIED:20190909T144542Z
UID:6431-1568188800-1568221200@scienceinboston.com
SUMMARY:Physicochemical Properties Workshop
DESCRIPTION:This workshop will foster discussion around techniques for measuring physicochemical properties and their applications in drug discovery.\n\n\n\n\n\n\nAbout this Event\n\n\nWORKSHOP SCHEDULE \n8:00 am – 9:00 am: Registration and Breakfast \n9:00 am – 9:30 am: Opening Remarks and Introductions \n9:30 am – 10:15 am: Franco Lombardo\, Senior Director of DMPK and Bioanalysis\, Alkermes – Perspectives on the Use of PhysChem in Lead Development \n10:15 am – 10:30 am: Coffee Break \n10:30 am – 11:15 am: Giulia Caron\, Professor in Medicinal Chemistry\, Expert in Molecular Properties\, University of Turin – Beyond Rule of 5 Space \n11:15 am – 12:00 pm: Attendee and Panel Discussion: How are Physicochemical Properties used in the Pharmaceutical Industry? \n12:00 pm – 1:00 pm: Lunch \n1:00 pm – 1:30 pm: Sarah St. John\, Pharma Business Development Manager\, Phenomenex– Use of Chromatographic Support to Highlight Interactions \n1:30 pm – 2:15 pm: Attendee and Panel Discussion: Potential Interest in New Descriptors\, New Techniques\, Need for Additional Tools\, Higher Throughput…? \n2:15 pm – 2:30 pm: Coffee Break \n2:30 pm – 3:00 pm: Gilles Goetz\, Principal Scientist\, Pfizer Inc. – New Techniques such as EPSA \n3:00 pm – 3:30 pm: Simone Sciabola\, Principal Scientist\, Biogen – Use of In Silico Tools\, with Applications on EPSA Model \n3:30 pm – 4:00 pm: Closing Remarks \n4:00 pm – 5:00 pm: Networking time \nQuestions? Please contact: \nKate Favre\, Senior Account Manager\, Analiza \nkate.favre@analiza.com \n(440) 241-4196 \n\n\nPresented by: \n\n\n\nPlease visit our website! www.analiza.com
URL:https://scienceinboston.com/event/physicochemical-properties-workshop/
LOCATION:Hilton Garden Inn Boston/Waltham\, 450 Totten Pond Road\, Waltham\, MA\, 02451\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190911T080000
DTEND;TZID=America/New_York:20190911T170000
DTSTAMP:20190909T144542Z
CREATED:20190909T144542Z
LAST-MODIFIED:20190909T144542Z
UID:27330-1568188800-1568221200@scienceinboston.com
SUMMARY:Physicochemical Properties Workshop
DESCRIPTION:This workshop will foster discussion around techniques for measuring physicochemical properties and their applications in drug discovery.\n\n\n\n\n\n\nAbout this Event\n\n\nWORKSHOP SCHEDULE \n8:00 am – 9:00 am: Registration and Breakfast \n9:00 am – 9:30 am: Opening Remarks and Introductions \n9:30 am – 10:15 am: Franco Lombardo\, Senior Director of DMPK and Bioanalysis\, Alkermes – Perspectives on the Use of PhysChem in Lead Development \n10:15 am – 10:30 am: Coffee Break \n10:30 am – 11:15 am: Giulia Caron\, Professor in Medicinal Chemistry\, Expert in Molecular Properties\, University of Turin – Beyond Rule of 5 Space \n11:15 am – 12:00 pm: Attendee and Panel Discussion: How are Physicochemical Properties used in the Pharmaceutical Industry? \n12:00 pm – 1:00 pm: Lunch \n1:00 pm – 1:30 pm: Sarah St. John\, Pharma Business Development Manager\, Phenomenex– Use of Chromatographic Support to Highlight Interactions \n1:30 pm – 2:15 pm: Attendee and Panel Discussion: Potential Interest in New Descriptors\, New Techniques\, Need for Additional Tools\, Higher Throughput…? \n2:15 pm – 2:30 pm: Coffee Break \n2:30 pm – 3:00 pm: Gilles Goetz\, Principal Scientist\, Pfizer Inc. – New Techniques such as EPSA \n3:00 pm – 3:30 pm: Simone Sciabola\, Principal Scientist\, Biogen – Use of In Silico Tools\, with Applications on EPSA Model \n3:30 pm – 4:00 pm: Closing Remarks \n4:00 pm – 5:00 pm: Networking time \nQuestions? Please contact: \nKate Favre\, Senior Account Manager\, Analiza \nkate.favre@analiza.com \n(440) 241-4196 \n\n\nPresented by: \n\n\n\nPlease visit our website! www.analiza.com
URL:https://scienceinboston.com/event/physicochemical-properties-workshop-2/
LOCATION:Hilton Garden Inn Boston/Waltham\, 450 Totten Pond Road\, Waltham\, MA\, 02451\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190910T114500
DTEND;TZID=America/New_York:20190910T130000
DTSTAMP:20190821T151231Z
CREATED:20190821T151231Z
LAST-MODIFIED:20190821T151231Z
UID:6297-1568115900-1568120400@scienceinboston.com
SUMMARY:From Bedside to Bench—Streamlined Workflow for Disease-modeling Using Patient-specific iPSC-derived Neurons.
DESCRIPTION:Join us and fellow scientists for lunch and a seminar on streamlining your workflow for disease modeling using patient-specific iPSC-derived neurons. The seminar will be held at STEMCELL Technologies’ office in Cambridge\, MA and feature the Assistant Director of Human Neuron Differentiation Services at Boston Children’s Hospital’s Human Neuron Core\, Dr. Ivy Pin-Fang Chen. Complimentary lunch will be provided. \nSpace is limited. RSVP before Sep 3 to reserve your spot! \n\n\n\n\n\n\nIvy Pin-Fang Chen\, PhD\nAssistant Director\, Human Neuron Differentiation Services\nHuman Neuron Core\, Boston Children’s Hospital\n\n\n\n\n\n\n\nFrom Bedside to Bench—Streamlined Workflow for Disease-modeling Using Patient-specific iPSC-derived Neurons.Tuesday\, Sep 10\, 2019 | 11:45 a.m. – 1:00 p.m. \nLocationSTEMCELL Technologies Inc. Cambridge Office\n222 Third Street\, Suite 2323\, Cambridge\, MA
URL:https://scienceinboston.com/event/from-bedside-to-bench-streamlined-workflow-for-disease-modeling-using-patient-specific-ipsc-derived-neurons/
LOCATION:STEMCELL Tech\, Suite 2323-222 Third Street\, Cambridge\, MA\, 02142\, United States
ORGANIZER;CN="STEMCELL Technologies":MAILTO:info@stemcell.com
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190910T114500
DTEND;TZID=America/New_York:20190910T130000
DTSTAMP:20190821T151231Z
CREATED:20190821T151231Z
LAST-MODIFIED:20190821T151231Z
UID:27324-1568115900-1568120400@scienceinboston.com
SUMMARY:From Bedside to Bench—Streamlined Workflow for Disease-modeling Using Patient-specific iPSC-derived Neurons.
DESCRIPTION:Join us and fellow scientists for lunch and a seminar on streamlining your workflow for disease modeling using patient-specific iPSC-derived neurons. The seminar will be held at STEMCELL Technologies’ office in Cambridge\, MA and feature the Assistant Director of Human Neuron Differentiation Services at Boston Children’s Hospital’s Human Neuron Core\, Dr. Ivy Pin-Fang Chen. Complimentary lunch will be provided. \nSpace is limited. RSVP before Sep 3 to reserve your spot! \n\n\n\n\n\n\nIvy Pin-Fang Chen\, PhD\nAssistant Director\, Human Neuron Differentiation Services\nHuman Neuron Core\, Boston Children’s Hospital\n\n\n\n\n\n\n\nFrom Bedside to Bench—Streamlined Workflow for Disease-modeling Using Patient-specific iPSC-derived Neurons.Tuesday\, Sep 10\, 2019 | 11:45 a.m. – 1:00 p.m. \nLocationSTEMCELL Technologies Inc. Cambridge Office\n222 Third Street\, Suite 2323\, Cambridge\, MA
URL:https://scienceinboston.com/event/from-bedside-to-bench-streamlined-workflow-for-disease-modeling-using-patient-specific-ipsc-derived-neurons-2/
LOCATION:STEMCELL Tech\, Suite 2323-222 Third Street\, Cambridge\, MA\, 02142\, United States
ORGANIZER;CN="STEMCELL Technologies":MAILTO:info@stemcell.com
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T170000
DTEND;TZID=America/New_York:20190909T190000
DTSTAMP:20190909T143544Z
CREATED:20190909T143453Z
LAST-MODIFIED:20190909T143544Z
UID:6424-1568048400-1568055600@scienceinboston.com
SUMMARY:CyTOF Analysis Workshop Series
DESCRIPTION:Invited speakers from Dana-Farber Cancer Institute and Bluebird Bio will talk about panel validation and addressing batch effect.\n\n\n\n\n\n\nAbout this Event\n\n\nSpeaker: Emily Thrash\, PhD\, Scientist II\, Dana-Farber Cancer Institute\nBio: Experienced Cancer Immunologist with a proven history of developing clinical trial correlative studies. Highly skilled in Flow Cytometry and CyTOF\, especially with primary patient samples. Patient-oriented\, results-driven research professional with a Doctorate in Biomedical Sciences\, Immunology from The Ohio State University College of Medicine. \nAbstract: CyTOF is revolutionizing correlative clinical trial studies allowing for deeper immune-phenotyping compared to traditional flow cytometry. Leveraging CyTOF technology\, our group has previously identified biomarkers of response to anti-PD-1 therapy in melanoma patients. Building upon those studies\, we have developed two CyTOF panels 1) Adaptive (CPB-A) and 2) Innate (CPB-I) that identify immune cell subsets and test biomarkers for response and resistance in patients receiving anti-PD-1 therapy. Here we present the validation of these panels\, as well as our method pipeline for CyTOF panel development. \nSpeaker: Brandon Nguyen\, Sr. Associate Scientist I\, Bluebird Bio\nAbstract: Mass Cytometry presents a unique opportunity to look at 40 antigens at once on a single cell basis\, this is particularly useful when trying to phenotypically characterize a cellular drug product. Currently at bluebird bio there are three clinical phase cellular drug products that leverage autologous CD34+ hematopoietic stem cells edited with lentiviral vector. Because hematopoiesis is a very fluid landscape\, we have developed a classification method to divide the CD34+ drug product into lineage specific progenitors and precursors with the help of high dimensional clustering. This characterization data set can then be used for correlative studies within each clinical trial and across multiple clinical trials. However\, in order to ensure data integrity for meaningful comparative studies a reference must be used to track staining consistency of each antibody. This was found to be necessary as batch effects played an important role into the potential skewing of high dimensional analysis. Overall\, longitudinal studies are a challenge due to batch specific staining variation\, however the variation can be minimized by tracking a reference cell bank and strategic optimization.
URL:https://scienceinboston.com/event/cytof-analysis-workshop-series/
LOCATION:Bluebird Bio\, 60 Binney Street\, Cambridge\, MA\, 02142\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T170000
DTEND;TZID=America/New_York:20190909T190000
DTSTAMP:20190909T143453Z
CREATED:20190909T143453Z
LAST-MODIFIED:20190909T143453Z
UID:27327-1568048400-1568055600@scienceinboston.com
SUMMARY:CyTOF Analysis Workshop Series
DESCRIPTION:Invited speakers from Dana-Farber Cancer Institute and Bluebird Bio will talk about panel validation and addressing batch effect.\n\n\n\n\n\n\nAbout this Event\n\n\nSpeaker: Emily Thrash\, PhD\, Scientist II\, Dana-Farber Cancer Institute\nBio: Experienced Cancer Immunologist with a proven history of developing clinical trial correlative studies. Highly skilled in Flow Cytometry and CyTOF\, especially with primary patient samples. Patient-oriented\, results-driven research professional with a Doctorate in Biomedical Sciences\, Immunology from The Ohio State University College of Medicine. \nAbstract: CyTOF is revolutionizing correlative clinical trial studies allowing for deeper immune-phenotyping compared to traditional flow cytometry. Leveraging CyTOF technology\, our group has previously identified biomarkers of response to anti-PD-1 therapy in melanoma patients. Building upon those studies\, we have developed two CyTOF panels 1) Adaptive (CPB-A) and 2) Innate (CPB-I) that identify immune cell subsets and test biomarkers for response and resistance in patients receiving anti-PD-1 therapy. Here we present the validation of these panels\, as well as our method pipeline for CyTOF panel development. \nSpeaker: Brandon Nguyen\, Sr. Associate Scientist I\, Bluebird Bio\nAbstract: Mass Cytometry presents a unique opportunity to look at 40 antigens at once on a single cell basis\, this is particularly useful when trying to phenotypically characterize a cellular drug product. Currently at bluebird bio there are three clinical phase cellular drug products that leverage autologous CD34+ hematopoietic stem cells edited with lentiviral vector. Because hematopoiesis is a very fluid landscape\, we have developed a classification method to divide the CD34+ drug product into lineage specific progenitors and precursors with the help of high dimensional clustering. This characterization data set can then be used for correlative studies within each clinical trial and across multiple clinical trials. However\, in order to ensure data integrity for meaningful comparative studies a reference must be used to track staining consistency of each antibody. This was found to be necessary as batch effects played an important role into the potential skewing of high dimensional analysis. Overall\, longitudinal studies are a challenge due to batch specific staining variation\, however the variation can be minimized by tracking a reference cell bank and strategic optimization.
URL:https://scienceinboston.com/event/cytof-analysis-workshop-series-2/
LOCATION:Bluebird Bio\, 60 Binney Street\, Cambridge\, MA\, 02142\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T080000
DTEND;TZID=America/New_York:20190912T200000
DTSTAMP:20190816T142215Z
CREATED:20190816T142215Z
LAST-MODIFIED:20190816T142215Z
UID:6203-1568016000-1568318400@scienceinboston.com
SUMMARY:Biotech Week Boston
DESCRIPTION:Biotech Week Boston is dedicated to accelerating the business of biotechnology through new ideas\, science\, technology and partnerships to make a positive impact on patient health. \nYou’ll find thought-leaders and potential partners from discovery\, financing\, manufacturing\, clinical trials\, who can help drive you closer to success. It’s an unparalleled opportunity to meet and do business with those who are shaping our industry’s future\, from researchers and investors\, to CEOs and founders. \nAdd a dazzling awards party\, and an evening of rock and roll\, Biotech Week Boston is also the convergence of business and fun.
URL:https://scienceinboston.com/event/biotech-week-boston/
LOCATION:Boston Convention and Exhibition Center (BCEC)\, 415 Summer St.\, Boston\, MA\, 02210\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T080000
DTEND;TZID=America/New_York:20190912T200000
DTSTAMP:20190816T142215Z
CREATED:20190816T142215Z
LAST-MODIFIED:20190816T142215Z
UID:27314-1568016000-1568318400@scienceinboston.com
SUMMARY:Biotech Week Boston
DESCRIPTION:Biotech Week Boston is dedicated to accelerating the business of biotechnology through new ideas\, science\, technology and partnerships to make a positive impact on patient health. \nYou’ll find thought-leaders and potential partners from discovery\, financing\, manufacturing\, clinical trials\, who can help drive you closer to success. It’s an unparalleled opportunity to meet and do business with those who are shaping our industry’s future\, from researchers and investors\, to CEOs and founders. \nAdd a dazzling awards party\, and an evening of rock and roll\, Biotech Week Boston is also the convergence of business and fun.
URL:https://scienceinboston.com/event/biotech-week-boston-2/
LOCATION:Boston Convention and Exhibition Center (BCEC)\, 415 Summer St.\, Boston\, MA\, 02210\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T080000
DTEND;TZID=America/New_York:20190912T170000
DTSTAMP:20190815T152747Z
CREATED:20190815T152715Z
LAST-MODIFIED:20190815T152747Z
UID:6193-1568016000-1568307600@scienceinboston.com
SUMMARY:Ergonomics and Human Factors: Strategic Solutions for Workplace Safety and Health
DESCRIPTION:Overview\n\nWork-related musculoskeletal disorders (MSDs) are a leading cause of employee injury and illness across industries and occupations. Fortunately\, work-related MSDs and their associated costs can be prevented through the effective application of ergonomic principles. \nThis applied program brings together professionals from across industries and sectors to prevent work-related musculoskeletal disorders and improve workplace health and safety through ergonomics. Ergonomics and Human Factors explores both the technical skills required to perform job assessments and the organizational factors which contribute to successful ergonomics programs. \nParticipants will complete this program ready to control health and performance problems through ergonomic interventions\, optimize their organization’s ergonomics program\, and improve employee health and safety. \nImprove Employee Health and Safety \nWith a focus on improving worker health and safety\, this program offers practical advice for implementing and optimizing workplace ergonomics programs. In addition\, the technical skills required for occupational ergonomic interventions are explored through lectures\, group work\, and in-depth discussions. This course is unique in considering both the public health and industry perspectives. \nNew Office Ergonomics Sessions \nPoorly designed work stations\, bad work habits\, and prolonged sitting can all have serious adverse health effects. With much of the American workforce performing sedentary work at a desk all day\, office ergonomics has taken on new levels of importance. This course now includes an expanded focus on office ergonomics to address these challenges. New sessions include: \n\nSit Stand Desks and the Necessary Training\nConsiderations for Standing Work\nPhysiology of Sitting\, Standing\, and Walking-Integration of Treadmills to Improve Workstations\nReview of the Evidence for Workstations\nSystem’s Approaches to Combating the Sedentary Workplace\n\nCourse Website
URL:https://scienceinboston.com/event/ergonomics-and-human-factors-strategic-solutions-for-workplace-safety-and-health/
LOCATION:Harvard Longwood Campus\, Boston\, MA\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T080000
DTEND;TZID=America/New_York:20190912T170000
DTSTAMP:20190815T152715Z
CREATED:20190815T152715Z
LAST-MODIFIED:20190815T152715Z
UID:27311-1568016000-1568307600@scienceinboston.com
SUMMARY:Ergonomics and Human Factors: Strategic Solutions for Workplace Safety and Health
DESCRIPTION:Overview\n\nWork-related musculoskeletal disorders (MSDs) are a leading cause of employee injury and illness across industries and occupations. Fortunately\, work-related MSDs and their associated costs can be prevented through the effective application of ergonomic principles. \nThis applied program brings together professionals from across industries and sectors to prevent work-related musculoskeletal disorders and improve workplace health and safety through ergonomics. Ergonomics and Human Factors explores both the technical skills required to perform job assessments and the organizational factors which contribute to successful ergonomics programs. \nParticipants will complete this program ready to control health and performance problems through ergonomic interventions\, optimize their organization’s ergonomics program\, and improve employee health and safety. \nImprove Employee Health and Safety \nWith a focus on improving worker health and safety\, this program offers practical advice for implementing and optimizing workplace ergonomics programs. In addition\, the technical skills required for occupational ergonomic interventions are explored through lectures\, group work\, and in-depth discussions. This course is unique in considering both the public health and industry perspectives. \nNew Office Ergonomics Sessions \nPoorly designed work stations\, bad work habits\, and prolonged sitting can all have serious adverse health effects. With much of the American workforce performing sedentary work at a desk all day\, office ergonomics has taken on new levels of importance. This course now includes an expanded focus on office ergonomics to address these challenges. New sessions include: \n\nSit Stand Desks and the Necessary Training\nConsiderations for Standing Work\nPhysiology of Sitting\, Standing\, and Walking-Integration of Treadmills to Improve Workstations\nReview of the Evidence for Workstations\nSystem’s Approaches to Combating the Sedentary Workplace\n\nCourse Website
URL:https://scienceinboston.com/event/ergonomics-and-human-factors-strategic-solutions-for-workplace-safety-and-health-2/
LOCATION:Harvard Longwood Campus\, Boston\, MA\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T070000
DTEND;TZID=America/New_York:20190912T180000
DTSTAMP:20190815T154121Z
CREATED:20190815T153644Z
LAST-MODIFIED:20190815T154121Z
UID:6196-1568012400-1568311200@scienceinboston.com
SUMMARY:AI Applications for Drug Discovery and Development
DESCRIPTION:Connect with key stakeholders in pharma and biotech to transform scientific research based on better decision-making\, optimized innovation\, improved efficiency of clinical trials\, and new tool creation for physicians\, consumers\, insurers\, and regulators at this year’s AI conference. The program consists of two full days of case studies that will give you the opportunity to learn how to improve R&D productivity\, expedite timelines & identify better drug candidates from target identification right through to post market. The 3rd day\, September 12\, is a dedicated partnering day offering you the opportunity to meet with industry\, academia\, consortia\, associations and tech providers to discuss the hottest trends and innovation in pharma and healthcare to date. \nMassBio member companies can save 10% off the current rate when you register online with VIP code MASSBIO (new registrations only). For full program details and to register\, visit our website.
URL:https://scienceinboston.com/event/ai-applications-for-drug-discovery-and-development/
LOCATION:Boston Convention and Exhibition Center (BCEC)\, 415 Summer St.\, Boston\, MA\, 02210\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190909T070000
DTEND;TZID=America/New_York:20190912T180000
DTSTAMP:20190815T153644Z
CREATED:20190815T153644Z
LAST-MODIFIED:20190815T153644Z
UID:27313-1568012400-1568311200@scienceinboston.com
SUMMARY:AI Applications for Drug Discovery and Development
DESCRIPTION:Connect with key stakeholders in pharma and biotech to transform scientific research based on better decision-making\, optimized innovation\, improved efficiency of clinical trials\, and new tool creation for physicians\, consumers\, insurers\, and regulators at this year’s AI conference. The program consists of two full days of case studies that will give you the opportunity to learn how to improve R&D productivity\, expedite timelines & identify better drug candidates from target identification right through to post market. The 3rd day\, September 12\, is a dedicated partnering day offering you the opportunity to meet with industry\, academia\, consortia\, associations and tech providers to discuss the hottest trends and innovation in pharma and healthcare to date. \nMassBio member companies can save 10% off the current rate when you register online with VIP code MASSBIO (new registrations only). For full program details and to register\, visit our website.
URL:https://scienceinboston.com/event/ai-applications-for-drug-discovery-and-development-2/
LOCATION:Boston Convention and Exhibition Center (BCEC)\, 415 Summer St.\, Boston\, MA\, 02210\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190906T113000
DTEND;TZID=America/New_York:20190906T143000
DTSTAMP:20190815T152807Z
CREATED:20190815T151253Z
LAST-MODIFIED:20190815T152807Z
UID:6192-1567769400-1567780200@scienceinboston.com
SUMMARY:Poretta & Orr Lunch & Learn: Maximize Convention Marketing Results - Successful Strategies for Biotechs - Pre-Launch Through Maturity
DESCRIPTION:Sometimes you just don’t know what you don’t know. If you work for a bio start-up or a company that is launching a new drug or device be sure you start thinking of your marketing end game right out of the gate! Knowing where you want to end up is vital to creating a successful strategy from the start. So mark your calendars now! Join MassBio member Poretta & Orr for an informative and interactive Lunch & Learn as we discuss the strategy behind a successful framework for convention planning\, including identification of essential partners and their roles. \n\nRob Metz\, Senior Vice President\, Global Business Operations & Chief Compliance Officer at Horizon Therapeutics is showcased in video clips and interviews that highlight Horizon Therapeutics strategic use of conventions through several phases of company growth and product life cycle.\nA review of best practices relating to conventions\, pre-launch and launch phases is reviewed.\nBest practices pertaining to planning and program evaluation is also a critical component of a successful convention marketing program and discussed.\nAgency collaboration processes and success stories are shared.\n\nRemember\, having a strategy from the beginning is vital to successful\, creative and memorable convention and exhibit marketing. Come ask your questions\, enjoy a delicious lunch and let’s get acquainted!
URL:https://scienceinboston.com/event/poretta-orr-lunch-learn-maximize-convention-marketing-results-successful-strategies-for-biotechs-pre-launch-through-maturity/
LOCATION:MassBio\, 300 Technology Square 8th Fl\, Cambridge\, MA\, 02139\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190906T113000
DTEND;TZID=America/New_York:20190906T143000
DTSTAMP:20190815T151253Z
CREATED:20190815T151253Z
LAST-MODIFIED:20190815T151253Z
UID:27310-1567769400-1567780200@scienceinboston.com
SUMMARY:Poretta & Orr Lunch & Learn: Maximize Convention Marketing Results - Successful Strategies for Biotechs - Pre-Launch Through Maturity
DESCRIPTION:Sometimes you just don’t know what you don’t know. If you work for a bio start-up or a company that is launching a new drug or device be sure you start thinking of your marketing end game right out of the gate! Knowing where you want to end up is vital to creating a successful strategy from the start. So mark your calendars now! Join MassBio member Poretta & Orr for an informative and interactive Lunch & Learn as we discuss the strategy behind a successful framework for convention planning\, including identification of essential partners and their roles. \n\nRob Metz\, Senior Vice President\, Global Business Operations & Chief Compliance Officer at Horizon Therapeutics is showcased in video clips and interviews that highlight Horizon Therapeutics strategic use of conventions through several phases of company growth and product life cycle.\nA review of best practices relating to conventions\, pre-launch and launch phases is reviewed.\nBest practices pertaining to planning and program evaluation is also a critical component of a successful convention marketing program and discussed.\nAgency collaboration processes and success stories are shared.\n\nRemember\, having a strategy from the beginning is vital to successful\, creative and memorable convention and exhibit marketing. Come ask your questions\, enjoy a delicious lunch and let’s get acquainted!
URL:https://scienceinboston.com/event/poretta-orr-lunch-learn-maximize-convention-marketing-results-successful-strategies-for-biotechs-pre-launch-through-maturity-2/
LOCATION:MassBio\, 300 Technology Square 8th Fl\, Cambridge\, MA\, 02139\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190906T083000
DTEND;TZID=America/New_York:20190906T180000
DTSTAMP:20190816T142747Z
CREATED:20190816T142747Z
LAST-MODIFIED:20190816T142747Z
UID:6209-1567758600-1567792800@scienceinboston.com
SUMMARY:2nd Annual Dana-Farber Chemical Biology Symposium
DESCRIPTION:We are approaching our capacity for registered attendees at this time! Please add your name to the wait list through EventBrite and we will let you know if space opens up!\n\nWe are delighted to welcome you to the 2nd Annual Dana-Farber Cancer Institute (DFCI) Chemical Biology Symposium! \nThis symposium aims to bring together speakers representing a diverse range of chemical biology research interests\, and highlight important insights\, developments\, and contributions to this unique field. We are excited to include an afternoon career panel discussion in addition to scientific talks. This day-long event is free to attend and open to the public. \nEarly evening poster session and reception to follow talks and afternoon career panel. \nRegistered attendees are also invited to submit poster abstracts here. \nAbstract deadline: August 19\, 2019 \nEvent Agenda\n8:00 – 8:30 AM Arrival and Registration (Coffee will be provided) \n8:30 – 8:45 AM Welcome Remarks \n8:45 – 9:30 AM Keynote Address\nMarion Dorsch \, Ph.D.\, Chief Scientific Officer\, Blueprint Medicines\n“Unlocking the full potential of kinase medicines: highly selective therapies for genomically defined diseases”\n9:30 – 10:00 AM Katya Marjon\, Agios “Targeting MAT2A in MTAP-deleted Cancers.” \n10:00 – 10:30 AM Sloan Devlin\, Harvard Medical School “Bacterial modifications of host metabolites alter host physiology” \n10:30 – 11:00 AM\, Coffee Break\, Jimmy Fund Auditorium Lobby \n11:00 – 11:30 AM Nathalie Agar\, Brigham And Women’s Hospital and Harvard Medical School \n11:30 AM – 12:00 PM Jeremy Jenkins\, Novartis Institute for BioMedical Research (NIBR)\, “Technology advances for characterizing compound MOA” \n12:00 – 1:00 PM Lunch on your own \n1:00 – 1:30 PM Angela Koehler\, Koch Institute at MIT\, “Attenuating Oncogenic Transcription with Small Molecules” \n1:30 – 2:00 PM Eric Fischer\, Dana-Farber Cancer Institute and Harvard Medical School “Principles of small molecule mediated ubiquitin ligase targeting” \n2:00 – 3:00 PM Career Panel Discussion: Christopher Browne (AstraZeneca)\, Janet Ralbovsky (Dana-Farber)\, Mishtu Dey (Cell Press)\, and Dora Carrico-Moniz (Wellesley College) \n3:00 – 3:15 PM Coffee Break\, Jimmy Fund Auditorium Lobby \n3:15 – 4:00 PM Keynote Address\nGarry Nolan\, Ph.D.\, Stanford University School of Medicine\n“Pathology from the molecular scale on up”\n4:00 – 4:05 PM Closing Remarks \n4:05 – 6:00 PM Poster Reception with Light Refreshments\, Yawkey Conference Center \n(submit your posters here) \nTo learn more about this event\, email the DFCI Chemical Biology Program at chemical_biology@dfci.harvard.edu\, or follow us on Twitter at @DFCI_ChemBio #DFCIChemBio2019 \nTo learn more about Chemical Biology @DFCI visit our website. \nDownload our event flyer here and spread the word! \nSee you there!
URL:https://scienceinboston.com/event/2nd-annual-dana-farber-chemical-biology-symposium/
LOCATION:Jimmy Fund Auditorium\, 35 Binney St\, Boston\, MA\, 02215\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20190906T083000
DTEND;TZID=America/New_York:20190906T180000
DTSTAMP:20190816T142747Z
CREATED:20190816T142747Z
LAST-MODIFIED:20190816T142747Z
UID:27316-1567758600-1567792800@scienceinboston.com
SUMMARY:2nd Annual Dana-Farber Chemical Biology Symposium
DESCRIPTION:We are approaching our capacity for registered attendees at this time! Please add your name to the wait list through EventBrite and we will let you know if space opens up!\n\nWe are delighted to welcome you to the 2nd Annual Dana-Farber Cancer Institute (DFCI) Chemical Biology Symposium! \nThis symposium aims to bring together speakers representing a diverse range of chemical biology research interests\, and highlight important insights\, developments\, and contributions to this unique field. We are excited to include an afternoon career panel discussion in addition to scientific talks. This day-long event is free to attend and open to the public. \nEarly evening poster session and reception to follow talks and afternoon career panel. \nRegistered attendees are also invited to submit poster abstracts here. \nAbstract deadline: August 19\, 2019 \nEvent Agenda\n8:00 – 8:30 AM Arrival and Registration (Coffee will be provided) \n8:30 – 8:45 AM Welcome Remarks \n8:45 – 9:30 AM Keynote Address\nMarion Dorsch \, Ph.D.\, Chief Scientific Officer\, Blueprint Medicines\n“Unlocking the full potential of kinase medicines: highly selective therapies for genomically defined diseases”\n9:30 – 10:00 AM Katya Marjon\, Agios “Targeting MAT2A in MTAP-deleted Cancers.” \n10:00 – 10:30 AM Sloan Devlin\, Harvard Medical School “Bacterial modifications of host metabolites alter host physiology” \n10:30 – 11:00 AM\, Coffee Break\, Jimmy Fund Auditorium Lobby \n11:00 – 11:30 AM Nathalie Agar\, Brigham And Women’s Hospital and Harvard Medical School \n11:30 AM – 12:00 PM Jeremy Jenkins\, Novartis Institute for BioMedical Research (NIBR)\, “Technology advances for characterizing compound MOA” \n12:00 – 1:00 PM Lunch on your own \n1:00 – 1:30 PM Angela Koehler\, Koch Institute at MIT\, “Attenuating Oncogenic Transcription with Small Molecules” \n1:30 – 2:00 PM Eric Fischer\, Dana-Farber Cancer Institute and Harvard Medical School “Principles of small molecule mediated ubiquitin ligase targeting” \n2:00 – 3:00 PM Career Panel Discussion: Christopher Browne (AstraZeneca)\, Janet Ralbovsky (Dana-Farber)\, Mishtu Dey (Cell Press)\, and Dora Carrico-Moniz (Wellesley College) \n3:00 – 3:15 PM Coffee Break\, Jimmy Fund Auditorium Lobby \n3:15 – 4:00 PM Keynote Address\nGarry Nolan\, Ph.D.\, Stanford University School of Medicine\n“Pathology from the molecular scale on up”\n4:00 – 4:05 PM Closing Remarks \n4:05 – 6:00 PM Poster Reception with Light Refreshments\, Yawkey Conference Center \n(submit your posters here) \nTo learn more about this event\, email the DFCI Chemical Biology Program at chemical_biology@dfci.harvard.edu\, or follow us on Twitter at @DFCI_ChemBio #DFCIChemBio2019 \nTo learn more about Chemical Biology @DFCI visit our website. \nDownload our event flyer here and spread the word! \nSee you there!
URL:https://scienceinboston.com/event/2nd-annual-dana-farber-chemical-biology-symposium-2/
LOCATION:Jimmy Fund Auditorium\, 35 Binney St\, Boston\, MA\, 02215\, United States
END:VEVENT
END:VCALENDAR