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DTSTART;VALUE=DATE:20210309
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SUMMARY:Viral Vectors for Gene Therapy – Manufacturing
DESCRIPTION:Course Description\n\nThis course teaches fundamental concepts in viral vectors for gene therapy and how to manufacture them. The course utilizes case studies and laboratory practices to demonstrate critical steps in the production of viral vectors.\n\nInstructors \n\nDavid McNally (MassBiologics)\nPhillip Tai (UMass Medical School)\nShekar Ganesa (MassBiologics)\nSangmook Lee (MassBiologics)\nTom Larkin (MassBiologics)\nMike Pietila (MassBiologics)\nGretchen Gee (MassBiologics)\nMatthew Burak (MassBiologics)\n\nTarget Audience \n\nScientist\, Senior Research Scientist\, Bioprocess Engineer\, or equivalent in Pharmaceuticals\, Biopharmaceuticals\n\nObjective \n\nUnderstand the major viral vector systems used for gene therapy and their advantages and disadvantages\nUnderstand the major expression systems used to manufacture viral vectors for use in gene therapy\nUnderstand the biochemistry of viral vectors\, their quality attributes and how to measure them\nDescribe some common pitfalls to avoid when processing viral vectors\nExecute transient transfection processes for the production of AAV using suspension HEK293 cells and process the material generated using filtration and chromatographic methods\n\nModules \n\nM1. Intro to Viral Vectors and their use in gene therapy\nM2. Upstream processing of Viral Vectors\nM3. Tour of labs and cGMP facility\nM4. Introduction/safety – hands on lab based work\nM5. Hands on lab work – upstream methods\nM6. Downstream processing of Viral Vectors – Chromatography\nM7. Downstream processing of Viral Vectors – Filtration\nM8. Regulatory Considerations for Gene Therapy Products\nM9. Hands on lab work – Downstream Methods\nM10. Analytical Methods\nM11. Analytical Case Studies\nM12. Hands-on lab work – Analytical Methods\nM13. Review of Analytical Data
URL:https://scienceinboston.com/event/viral-vectors-for-gene-therapy-manufacturing/
LOCATION:Online
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DTSTART;VALUE=DATE:20210309
DTEND;VALUE=DATE:20210312
DTSTAMP:20210301T181748Z
CREATED:20210301T181748Z
LAST-MODIFIED:20210301T181748Z
UID:27668-1615248000-1615507199@scienceinboston.com
SUMMARY:Viral Vectors for Gene Therapy – Manufacturing
DESCRIPTION:Course Description\n\nThis course teaches fundamental concepts in viral vectors for gene therapy and how to manufacture them. The course utilizes case studies and laboratory practices to demonstrate critical steps in the production of viral vectors.\n\nInstructors \n\nDavid McNally (MassBiologics)\nPhillip Tai (UMass Medical School)\nShekar Ganesa (MassBiologics)\nSangmook Lee (MassBiologics)\nTom Larkin (MassBiologics)\nMike Pietila (MassBiologics)\nGretchen Gee (MassBiologics)\nMatthew Burak (MassBiologics)\n\nTarget Audience \n\nScientist\, Senior Research Scientist\, Bioprocess Engineer\, or equivalent in Pharmaceuticals\, Biopharmaceuticals\n\nObjective \n\nUnderstand the major viral vector systems used for gene therapy and their advantages and disadvantages\nUnderstand the major expression systems used to manufacture viral vectors for use in gene therapy\nUnderstand the biochemistry of viral vectors\, their quality attributes and how to measure them\nDescribe some common pitfalls to avoid when processing viral vectors\nExecute transient transfection processes for the production of AAV using suspension HEK293 cells and process the material generated using filtration and chromatographic methods\n\nModules \n\nM1. Intro to Viral Vectors and their use in gene therapy\nM2. Upstream processing of Viral Vectors\nM3. Tour of labs and cGMP facility\nM4. Introduction/safety – hands on lab based work\nM5. Hands on lab work – upstream methods\nM6. Downstream processing of Viral Vectors – Chromatography\nM7. Downstream processing of Viral Vectors – Filtration\nM8. Regulatory Considerations for Gene Therapy Products\nM9. Hands on lab work – Downstream Methods\nM10. Analytical Methods\nM11. Analytical Case Studies\nM12. Hands-on lab work – Analytical Methods\nM13. Review of Analytical Data
URL:https://scienceinboston.com/event/viral-vectors-for-gene-therapy-manufacturing-2/
LOCATION:Online
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