Bayer will spend more than $30 million over the next five years to fund joint research projects with Brigham and Women’s Hospital (BWH) and Massachusetts General Hospital (MGH) at a new joint lab opened by the three to research new drug candidates to treat chronic lung diseases. The new joint lab is designed to combine Bayer’s capabilities in drug discovery…
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The Future of Mind Control

Charles M. Lieber and Shaun Patel, a faculty member at the Harvard Medical School and Massachusetts General Hospital, see a field — their own — at a tipping point. In a perspective titled “Precision Electronic Medicine,” published this month in Nature Biotechnology, they argue that neurotechnology is on the cusp of a major renaissance. “The next frontier is really the merging of human cognition…
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Multiple sclerosis is an autoimmune disease affecting both adults and children. It’s driven by “helper” T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord, degrading the protective myelin sheath that covers nerve fibers. But there are many different kinds of T helper cells, and up until now, no one knew which ones were the…
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One out of four adults with diabetes will ultimately develop kidney disease that can lead to kidney failure. These patients are often told that keeping their blood sugar levels under control should keep diabetic kidney disease (DKD) at bay. However, even when they do this, many patients still end up developing DKD. A new study that examined the genetics of…
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Our everyday lives rely on planned movement through the environment to achieve goals. A new study by MIT neuroscientists at the Picower Institute for Learning and Memory at MIT identifies a well-connected brain region as a crucial link between circuits guiding goal-directed movement and motivated behavior. Published Sept. 19 in Current Biology, the research shows that the lateral septum (LS), a…
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Drug-eluting contact lenses, which gradually release drugs into the eye, offer a promising alternative to daily eye drops, which can be unpleasant and hard for patients to properly administer. In a 2016 pre-clinical study of glaucoma, the engineered lenses lowered eye pressure at least as well as daily eye drops. New work from Massachusetts Eye and Ear and Boston Children’s Hospital…
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Massachusetts General Hospital will soon start the first clinical trial that simultaneously tests multiple potential ALS medicines in the hopes of getting results faster at lower costs. The elite Boston teaching hospital plans to launch the first “platform trial” in early 2020 at the Sean M. Healey & AMG Center for ALS, which was founded last year with $40 million…
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A new study led by Harvard Medical School researchers at the MassGeneral Hospital for Children has found that adolescent sleep timing preferences and patterns should be considered risk factors for obesity and cardiometabolic health, and that the effects are greater in girls than in boys. Poor quality and short duration of sleep are known to increase obesity and cardiometabolic risk…
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Sepsis, an extreme immune response to infection, has no specific treatment and is a leading cause of hospital deaths. As part of their care, patients often undergo imaging procedures and surgery to pinpoint and help eliminate the infection. New preclinical findings in mice suggest that the choice of general anesthetic used for these procedures can influence sepsis outcomes. Quite separate…
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Major physical changes occurred in the human heart as people shifted from hunting and foraging to farming and modern life.  As a result, human hearts are now less “ape-like” and better suited to endurance types of activity. But that also means those who lead sedentary lives are at greater risk for heart disease. Those are the main conclusions from a…
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